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- Title
Hallazgos histológicos de la cóclea de cobayos expuestos al ruido y tratados con vasodilatador y vitaminas.
- Authors
María C., Navarro-Meza; Eduardo, Orozco-Chávez; Sergio I., Díaz-Rodríguez; José A., González-González; del Toro María de L., Borjas; David E., Carmona-Navarro
- Abstract
Introduction: Noise-induced hearing loss affects 20 million workers. There is no drug of choice to reduce the cochlear damage induced by this physical. Material and Methods: Comparative experimental study, which included nine guinea pigs that were grouped into three groups: the first, received a vasodilator (ginkgo biloba); the second received vitamin A, C, E and magnesium; meanwhile the thirdgroup, received saline. All guinea pigs were exposed to 80 decibelsfor eight hours a dayfor seven days; Afterwards, the cochlea were analized and a comparison of the groups according to the Covell and Davis classification was made. Results: When comparing the vasodilator against placebo, wefound a value of p <0.002 in favor of thefirst; but when comparing the vasodilator against vitamins, we did not find statistical significance. Discussion: We propose to carry out more studies to verify if the administration of vasodilators couldprotect the human ear and thus be established as a prophylactic medicine in workers exposed to noise.
- Subjects
DAVIS (Calif.); GINKGO; GUINEA pigs; VITAMIN A; DEAFNESS; COMPARATIVE method
- Publication
Revista Médica MD, 2019, Vol 10, Issue 3, p210
- ISSN
2007-8188
- Publication type
Article