We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Stanovení jaterní steatózy MR spektroskopickými metodami PRESS, STEAM a HISTO.
- Authors
Hájek, Milan; Dezortová, Monika; Burian, Martin; Dusilová, Tereza; Kovář, Jan; Trunečka, Pavel; Šedivý, Petr
- Abstract
Aim: To compare MR spectroscopic methods for steatosis determination by PRESS, STEAM and HISTO sequences on 3T TRIO and VIDA tomographs. Method: 1H MR spectra of the liver of volunteers were measured on 3T tomographs Siemens TRIO and VIDA (45/25 subjects). The sequences PRESS with TE = 30/33 ms, STEAM with TE = 20/33 ms and the HISTO method with TE = 12-72 ms were used. The same sequences were used to determine T2 of lipids and water. The spectra were processed using the LCModel method. Fractional (FF) and volume (HFC) fractions (%) were corrected for individual and mean T2 values. Correlation, regression and Bland-Altman data analyses were performed. Results: Relaxation times T2 reduce FF and HFC values by up to approx. 47%. Regression analysis and Bland-Altman graphs show that the parameters obtained by PRESS, STEAM and HISTO techniques with short TE are comparable on VIDA. Mean T2 values of lipids between 45 and 53 ms and T2 of water between 24 and 31 ms were measured. HISTO FF cut-off values for the degree of steatosis in transplant patients were set in the following ranges:S0: < 0.8%; S1: 0.81-6.2%; S2: 6.21-16.5%; S3: > 16.5%. Conclusion: The obtained FF and HFC values are sensitive to T2 corrections. Bland-Altman's graphs indicate good agreement among STEAM, PRESS and HISTO methods. Limit values for the steatosis degree in transplant patients from the result of the HISTO method agree with literature values.
- Subjects
REGRESSION analysis; FATTY degeneration; DATA analysis; LIVER; LIPIDS
- Publication
Czech Radiology / Ceska Radiologie, 2020, Vol 74, Issue 3, p211
- ISSN
1210-7883
- Publication type
Article