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- Title
Contrast-enhanced ultrasonography: advance and current status in abdominal imaging.
- Authors
Yong Eun Chung; Ki Whang Kim
- Abstract
In the field of contrast-enhanced ultrasonography (US), contrast agents are classified as either first- or second-generation agents depending on the gas within the microbubbles. In the case of first-generation contrast agents, a high-mechanical-index technique is used and only intermittent scanning is possible due to the early destruction of the microbubbles during the scanning. The use of second-generation contrast agents in a low-mechanical-index technique enables continuous scanning. Besides the detection and characterization of focal liver lesions, contrastenhanced US is helpful in the monitoring of radiofrequency ablation therapy and in the targeting step of an US-guided biopsy. Recently, there has been a demand for new criteria to evaluate the treatment response obtained using anti-angiogenic agents because morphologic criteria alone may not reflect the treatment response of the tumor and contrast-enhanced US can provide quantitative markers of tissue perfusion. In spite of the concerns related to its cost-effectiveness, contrast-enhanced US has the potential to be more widely used as a complimentary tool or to substitute the current imaging modalities in some occasions.
- Subjects
CONTRAST-enhanced ultrasound; ULTRASONIC imaging of the abdomen; DIAGNOSIS of abdominal diseases
- Publication
Ultrasonography, 2015, Vol 34, Issue 1, p3
- ISSN
2288-5919
- Publication type
Article
- DOI
10.14366/usg.14034