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- Title
Efficacy study of a topical treatment with a plant extract with antibiofilm activities using an in vivo model of canine superficial pyoderma.
- Authors
Bäumer, Wolfgang; Jacobs, Megan; Tamamoto‐Mochizuki, Chie
- Abstract
Canine pyoderma, a bacterial infection of the skin most commonly caused by staphylococci, is among the frequently encountered dermatological conditions in dogs. W16P576 extract also inhibited bacterial biofilms by >90% at this concentration.[4] Therefore, it was hypothesized that topical administration of W16P576 would prevent or reduce lesion development induced by I S. pseudintermedius i in the canine model of pyoderma. However, comparison of lesion scores showed statistically significant differences between W16P576 application and the vehicle for both concentrations of inoculum, where vehicle-treated dogs had more severe lesions.
- Subjects
PLANT extracts; VETERINARY dermatology; OXACILLIN; ESSENTIAL fatty acids; DRUG resistance in microorganisms
- Publication
Veterinary Dermatology, 2020, Vol 31, Issue 2, p86
- ISSN
0959-4493
- Publication type
Article
- DOI
10.1111/vde.12808