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- Title
Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells.
- Authors
Lambert, Sarah; Lopez, Bernard S.
- Abstract
Presents a study that examined the impact of the RAD51 recombination pathway on recombination and mutagenesis induced by UV-C in mammalian cells. Benefits from the DNA double strand breaks; Paradigm for post-replication repair in Escherichia coli; Considerations that raise the question of the residual potential mutagenesis in a context defective in the alternative homologous recombination post-replication pathway.
- Subjects
GENETIC recombination; MUTAGENESIS; ESCHERICHIA coli; HOMOLOGY (Biology)
- Publication
Oncogene, 2002, Vol 21, Issue 25, p4065
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205535