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- Title
The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21).
- Authors
Kapoor, Rohit; Khunger, Jitender Mohan; Sharma, Atul; Sachdeva, Soumya
- Abstract
A 13-year-old female child presented with bilateral proptosis and subconjuctival hemorrhage of 2 months duration. Subsequently, the biopsy and peripheral smears confirmed the diagnosis of acute myeloid leukemia (AML). Recurrent cytogenetic translocation t(8:21) in AML associated with extramedullary manifestation; was discovered which is a rare event. Furthermore, myeloperoxidase negative blasts and periodic acid Schiff negative blasts in AML with t(8:21) is a very rare combination to the best of our knowledge.
- Subjects
HUMAN cytogenetics; CHROMOSOMAL translocation
- Publication
International Journal of Applied & Basic Medical Research, 2015, Vol 5, Issue 1, p76
- ISSN
2229-516X
- Publication type
Case Study
- DOI
10.4103/2229-516X.149256