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- Title
Method for Successfully Inducting Individuals Who Use Illicit Fentanyl Onto Buprenorphine/Naloxone.
- Authors
Antoine, Denis; Huhn, Andrew S.; Strain, Eric C.; Turner, Gavin; Jardot, Jasmyne; Hammond, Alexis S.; Dunn, Kelly E.
- Abstract
Background and Objectives: Individuals exposed to fentanyl are at risk of precipitated withdrawal using typical buprenorphine/naloxone induction procedures. Methods: This case series describes buprenorphine/naloxone inductions of four individuals who tested positive for fentanyl. Results: Buprenorphine‐precipitated withdrawal was observed in two individuals who completed a conventional buprenorphine/naloxone induction strategy. Two more individuals completed a revised buprenorphine/naloxone induction strategy that did not precipitate withdrawal. Discussion and Conclusion: Using multiple 2 mg doses of buprenorphine/naloxone in patients already in mild/moderate withdrawal improved outcomes. Scientific Significance: Persons who use illicit fentanyl might be less likely to experience precipitated withdrawal from this revised buprenorphine/naloxone induction strategy. (Am J Addict 2021;30:83–87)
- Subjects
NALOXONE; FENTANYL; BUPRENORPHINE
- Publication
American Journal on Addictions, 2021, Vol 30, Issue 1, p83
- ISSN
1055-0496
- Publication type
Article
- DOI
10.1111/ajad.13069