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- Title
Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence.
- Authors
Anton, Raymond F.; O'Malley, Stephanie S.; Ciraulo, Domenic A.; Cisler, Ron A.; Couper, David; Donovan, Dennis M.; Gastfriend, David R.; Hosking, James D.; Johnson, Bankole A.; LoCastro, Joseph S.; Longabaugh, Richard; Mason, Barbara J.; Mattson, Margaret E.; Miller, William R.; Pettinati, Helen M.; Randall, Carrie L.; Swift, Robert; Weiss, Roger D.; Williams, Lauren D.; Zweben, Allen
- Abstract
The article presents the details of a randomized controlled medical trial conducted to evaluate the efficacy of combined pharmacotherapies and behavioral interventions for alcohol dependence. The trial used two medications, naltrexone and acamprosate, along with combined behavioral therapies to treat alcoholism. The results showed that naltrexone both with and without combined behavioral therapies was efficacious while acamprosate proved to be noneffective when used alone or with combined behavioral therapies.
- Subjects
ALCOHOLISM treatment; DRUG abuse; SUBSTANCE abuse; BEHAVIOR therapy; ACAMPROSATE; ENDORPHIN receptors; DRUG receptors; REHABILITATION of people with alcoholism; THERAPEUTICS
- Publication
JAMA: Journal of the American Medical Association, 2006, Vol 295, Issue 17, p2003
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.295.17.2003