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- Title
Editorial: Tropism, Mapping, Modeling, or Therapy Using Canine Adenovirus Type 2 (CAV-2) Vectors in the CNS.
- Authors
Dopeso-Reyes, Iria Gonzalez; Wolff, Mathieu; Andrews, Melissa R.; Kremer, Eric J.
- Abstract
Keywords: CAV-2; neural circuit tracing; gene transfer; Parkinson's disease; coxsackievirus adenovirus receptor; retrograde transport; DREADDs; optogenetics EN CAV-2 neural circuit tracing gene transfer Parkinson's disease coxsackievirus adenovirus receptor retrograde transport DREADDs optogenetics N.PAG N.PAG 3 02/16/21 20210211 NES 210211 This Frontiers in Molecular Neuroscience Research Topic addresses tropism, mapping, modeling, and therapy using canine adenovirus (CAV-2) vectors in the CNS. i " E1/E3-deleted CAV-2 vectors have a cloning capacity >7 kbp, while helper-dependent CAV-2 vectors (HD-CAV2) have a cloning capacity up to 36 kbp (del Rio et al.).
- Subjects
VIRAL tropism; PERIPHERAL nervous system; DARDARIN; SYNAPSES; ADENOVIRUSES; NEURAL circuitry; TROPISMS
- Publication
Frontiers in Molecular Neuroscience, 2021, Vol 13, pN.PAG
- ISSN
1662-5099
- Publication type
Editorial
- DOI
10.3389/fnmol.2021.636476