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- Title
Quantitative Evaluation of the Normal Cervix, Cervical Cancer, and Cervical Precancerous Changes Via Real‐Time Shear Wave Elastography.
- Authors
Guo, Yan‐Jing; Yan, Xiao‐Jing; Zhao, Hai‐Xia; Wen, Xiao‐Duo; Wang, Jing; Du, Yuan‐Yuan; Wang, Nan; Yang, Yi
- Abstract
Objectives: The present study aims to evaluate the clinical application values of ultrasound real‐time shear wave elastography (SWE) in the diagnosis and differential diagnosis of cervical cancer (CC). Methods: A total of 285 married female patients were screened and divided into three groups according to the results of the pathological examination and the cervical ThinPrep cytologic test: 1) the CC group (n = 94); 2) the cervical intraepithelial neoplasia (CIN) group (n = 91); and 3) the normal control group (n = 100). The maximum Young's modulus (Emax), mean Young's modulus (Emean), minimum Young's modulus (Emin), and Young's modulus stability (Esd) in each group were measured and statistically analyzed. Results: There were no statistically significant differences in Emax, Emean, Emin, and Esd values between the anterior and posterior cervical walls, premenopausal and postmenopausal women, and nonparturient and parturient women in the normal control group. The Emax, Emean, Emin, and Esd values in the CIN group showed no statistically significant differences in different periods when compared with the control group. The differences between the normal control group and the CC group were statistically significant; the CC group showed no statistically significant differences in Emax, Emean, Emin, and Esd values at different clinical stages and in different pathological types. The cutoff value of Emax for CC diagnosis, which was of the highest accuracy (89.7%), was 43.48 kpa. Conclusion: Ultrasound real‐time SWE can be applied to CC diagnosis.
- Subjects
SHEAR waves; YOUNG'S modulus; CERVICAL cancer; CERVICAL intraepithelial neoplasia; ELASTOGRAPHY
- Publication
Journal of Ultrasound in Medicine, 2023, Vol 42, Issue 2, p345
- ISSN
0278-4297
- Publication type
Article
- DOI
10.1002/jum.15981