We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
An atypical subtrochanteric femoral fracture from pycnodysostosis: A lesson from nature.
- Authors
Yates, Christopher J.; Bartlett, Miriam J.; Ebeling, Peter R.
- Abstract
This case describes a man with an unusual cause of an atypical subtrochanteric fracture, pycnodysostosis. This condition results from mutations involving the cathepsin K gene. New antiresorptive treatments for osteoporosis inhibit the cathepsin K enzyme in osteoclasts. Therefore, there should be vigilant monitoring for the development of long-term complications noted to occur in diseases of reduced osteoclast function, including pycnodysostosis, in patients receiving these novel antiresorptive agents. © 2011 American Society for Bone and Mineral Research.
- Subjects
FEMUR injuries; OSTEOPOROSIS; BONE fractures; OSTEOCLASTS; BONE resorption
- Publication
Journal of Bone & Mineral Research, 2011, Vol 26, Issue 6, p1377
- ISSN
0884-0431
- Publication type
Article
- DOI
10.1002/jbmr.308