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- Title
Optimal tube current for lung cancer screening with low-dose spiral CT.
- Authors
Oguchi, K.; Sone, S.; Kiyono, K.; Takashima, S.; Maruyama, Y.; Hasegawa, M.; Feng, L.
- Abstract
<bold>Purpose: </bold>To determine the optimal tube current for spiral CT for lung cancer screening.<bold>Material and Methods: </bold>Low-dose spiral CT images from 20 subjects were obtained with 50 mA, 25 mA, 10 mA and 5 mA tube currents. The accuracy in detecting 21 nodules measuring 3 to 14 mm in diameter was tested using receiver operating characteristics (ROC) to determine the diagnostic accuracy and statistical significance.<bold>Results: </bold>Compared with 50 mA, 25 mA showed no statistical difference. A significant difference was seen between 50 mA and 5 mA images and between 25 mA and 10 mA images, in the detection of lung parenchymal nodular lesions.<bold>Conclusion: </bold>Approximately 25 mA is the optimal tube current for the detection of pulmonary nodules as it allows a reduction of the radiation dose without sacrificing diagnostic accuracy.
- Subjects
SPIRAL computed tomography; LUNG cancer diagnosis
- Publication
Acta Radiologica, 2000, Vol 41, Issue 4, p352
- ISSN
0284-1851
- Publication type
journal article
- DOI
10.1080/028418500127345451