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- Title
25‐hydroxyvitamin D and risk of atopic diseases and infections in early childhood.
- Authors
Brustad, Nicklas; Kim, Min; Skov, Frederikke; Schoos, Ann‐Marie; Stokholm, Jakob; Bønnelykke, Klaus; Chawes, Bo L.
- Abstract
In this study utilizing data from the large Danish COPSAC SB 2010 sb cohort, we found that high levels of 25(OH)D in early but not late childhood were associated with a reduced risk of AD, allergy, asthma exacerbations and infections during preschool-age with sex-specific associations. To the Editor, Low 25-hydroxyvitamin D (25(OH)D) is linked to increased risk of atopic diseases and infections in childhood,[[1]] however, longitudinal follow-up studies to identify potential windows for interventions are lacking. Details of the study have been published.[5] The diagnostic criteria of persistent wheeze, asthma, asthma exacerbations, lung function, atopic dermatitis (AD), allergic sensitization, rhinitis and number of infections are outlined in the Supplementary Material together with details of the statistical analysis.
- Subjects
WHEEZE; CHOLECALCIFEROL; CHEMILUMINESCENCE immunoassay
- Publication
Allergy, 2023, Vol 78, Issue 10, p2770
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.15759