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Long-Term Outcome and Treatment in Persistent and Transient Congenital Hyperinsulinism: A Finnish Population-Based Study.
Published in:
2021
By:
- Männistö, Jonna M. E.;
- Jääskeläinen, Jarmo;
- Otonkoski, Timo;
- Huopio, Hanna
Publication type:
journal article
Clinical and Genetic Characterization of 153 Patients with Persistent or Transient Congenital Hyperinsulinism.
Published in:
2020
By:
- Männistö, Jonna M E;
- Maria, Maleeha;
- Raivo, Joose;
- Kuulasmaa, Teemu;
- Otonkoski, Timo;
- Huopio, Hanna;
- Laakso, Markku
Publication type:
journal article
In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.
Published in:
2011
By:
- Henquin, Jean-Claude;
- Nenquin, Myriam;
- Sempoux, Christine;
- Guiot, Yves;
- Bellanné-Chantelot, Christine;
- Otonkoski, Timo;
- Lonlay, Pascale de;
- Nihoul-Fékété, Claire;
- Rahier, Jacques;
- Bellanné-Chantelot, Christine;
- de Lonlay, Pascale;
- Nihoul-Fékété, Claire
Publication type:
journal article
Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy.
Published in:
BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/102969
By:
- Hyvönen, Mervi E.;
- Dumont, Vincent;
- Tienari, Jukka;
- Lehtonen, Eero;
- Ustinov, Jarkko;
- Havana, Marika;
- Jalanko, Hannu;
- Otonkoski, Timo;
- Miettinen, Päivi J.;
- Lehtonen, Sanna
Publication type:
Article
Bacteriophage Mu integration in yeast and mammalian genomes.
Published in:
Nucleic Acids Research, 2008, v. 36, n. 22, p. e148, doi. 10.1093/nar/gkn801
By:
- Paatero, Anja O.;
- Turakainen, Hilkka;
- Happonen, Lotta J.;
- Olsson, Cia;
- Palomäki, Tiina;
- Pajunen, Maria I.;
- Meng, Xiaojuan;
- Otonkoski, Timo;
- Tuuri, Timo;
- Berry, Charles;
- Malani, Nirav;
- Frilander, Mikko J.;
- Bushman, Frederic D.;
- Savilahti, Harri
Publication type:
Article
Integrative genomics and transcriptomics analysis of human embryonic and induced pluripotent stem cells.
Published in:
BioData Mining, 2014, v. 7, n. 1, p. 15, doi. 10.1186/s13040-014-0032-2
By:
- Laurila, Kirsti;
- Autio, Reija;
- Kong, Lingjia;
- Närvä, Elisa;
- Hussein, Samer;
- Otonkoski, Timo;
- Lahesmaa, Riitta;
- Lähdesmäki, Harri
Publication type:
Article
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity.
Published in:
Nature Biotechnology, 2010, v. 28, n. 4, p. 371, doi. 10.1038/nbt.1615
By:
- Närvä, Elisa;
- Autio, Reija;
- Rahkonen, Nelly;
- Kong, Lingjia;
- Harrison, Neil;
- Kitsberg, Danny;
- Borghese, Lodovica;
- Itskovitz-Eldor, Joseph;
- Rasool, Omid;
- Dvorak, Petr;
- Hovatta, Outi;
- Otonkoski, Timo;
- Tuuri, Timo;
- Cui, Wei;
- Brüstle, Oliver;
- Baker, Duncan;
- Maltby, Edna;
- Moore, Harry D.;
- Benvenisty, Nissim;
- Andrews, Peter W.
Publication type:
Article
N-Glycolylneuraminic Acid Xenoantigen Contamination of Human Embryonic and Mesenchymal Stem Cells Is Substantially Reversible.
Published in:
Stem Cells, 2007, v. 25, n. 1, p. 197, doi. 10.1634/stemcells.2006-0444
By:
- HEISKANEN, ANNAMARI;
- SATOMAA, TERO;
- TIITINEN, SARI;
- LAITINEN, ANITA;
- MANNELIN, SIRKKA;
- IMPOLA, ULLA;
- MIKKOLA, MILLA;
- OLSSON, CIA;
- MILLER-PODRAZA, HALINA;
- BLOMQVIST, MARIA;
- OLONEN, ANNE;
- SALO, HANNA;
- LEHENKARI, PETRI;
- TUURI, TIMO;
- OTONKOSKI, TIMO;
- NATUNEN, JARI;
- SAARINEN, JUHANI;
- LAINE, JARMO
Publication type:
Article
Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease.
Published in:
Nature Genetics, 2014, v. 46, n. 8, p. 812, doi. 10.1038/ng.3040
By:
- Flanagan, Sarah E;
- Haapaniemi, Emma;
- Russell, Mark A;
- Caswell, Richard;
- Allen, Hana Lango;
- De Franco, Elisa;
- McDonald, Timothy J;
- Rajala, Hanna;
- Ramelius, Anita;
- Barton, John;
- Heiskanen, Kaarina;
- Heiskanen-Kosma, Tarja;
- Kajosaari, Merja;
- Murphy, Nuala P;
- Milenkovic, Tatjana;
- Seppänen, Mikko;
- Lernmark, Åke;
- Mustjoki, Satu;
- Otonkoski, Timo;
- Kere, Juha
Publication type:
Article
Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population.
Published in:
2016
By:
- Huopio, Hanna;
- Miettinen, Päivi J;
- Ilonen, Jorma;
- Nykänen, Päivi;
- Veijola, Riitta;
- Keskinen, Päivi;
- Näntö-Salonen, Kirsti;
- Vangipurapu, Jagadish;
- Raivo, Joose;
- Stančáková, Alena;
- Männistö, Jonna;
- Kuulasmaa, Teemu;
- Knip, Mikael;
- Otonkoski, Timo;
- Laakso, Markku
Publication type:
journal article
Restricted ethnic diversity in human embryonic stem cell lines.
Published in:
2010
By:
- Laurent, Louise C.;
- Nievergelt, Caroline M.;
- Lynch, Candace;
- Fakunle, Eyitayo;
- Harness, Julie V.;
- Schmidt, Uli;
- Galat, Vasiliy;
- Laslett, Andrew L.;
- Otonkoski, Timo;
- Keirstead, Hans S.;
- Schork, Andrew;
- Park, Hyun-Sook;
- Loring, Jeanne F.
Publication type:
Letter
Non-invasive quantification of stem cell-derived islet graft size and composition.
Published in:
Diabetologia, 2024, v. 67, n. 9, p. 1912, doi. 10.1007/s00125-024-06194-5
By:
- Lithovius, Väinö;
- Lahdenpohja, Salla;
- Ibrahim, Hazem;
- Saarimäki-Vire, Jonna;
- Uusitalo, Lotta;
- Montaser, Hossam;
- Mikkola, Kirsi;
- Yim, Cheng-Bin;
- Keller, Thomas;
- Rajander, Johan;
- Balboa, Diego;
- Barsby, Tom;
- Solin, Olof;
- Nuutila, Pirjo;
- Grönroos, Tove J.;
- Otonkoski, Timo
Publication type:
Article
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function.
Published in:
Diabetologia, 2024, v. 67, n. 8, p. 1642, doi. 10.1007/s00125-024-06163-y
By:
- Ibrahim, Hazem;
- Balboa, Diego;
- Saarimäki-Vire, Jonna;
- Montaser, Hossam;
- Dyachok, Oleg;
- Lund, Per-Eric;
- Omar-Hmeadi, Muhmmad;
- Kvist, Jouni;
- Dwivedi, Om P.;
- Lithovius, Väinö;
- Barsby, Tom;
- Chandra, Vikash;
- Eurola, Solja;
- Ustinov, Jarkko;
- Tuomi, Tiinamaija;
- Miettinen, Päivi J.;
- Barg, Sebastian;
- Tengholm, Anders;
- Otonkoski, Timo
Publication type:
Article
Maturation of beta cells: lessons from in vivo and in vitro models.
Published in:
Diabetologia, 2022, v. 65, n. 6, p. 917, doi. 10.1007/s00125-022-05672-y
By:
- Barsby, Tom;
- Otonkoski, Timo
Publication type:
Article
SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism.
Published in:
Diabetologia, 2021, v. 64, n. 3, p. 630, doi. 10.1007/s00125-020-05346-7
By:
- Lithovius, Väinö;
- Saarimäki-Vire, Jonna;
- Balboa, Diego;
- Ibrahim, Hazem;
- Montaser, Hossam;
- Barsby, Tom;
- Otonkoski, Timo
Publication type:
Article
Family history of type 2 diabetes and characteristics of children with newly diagnosed type 1 diabetes.
Published in:
Diabetologia, 2021, v. 64, n. 3, p. 581, doi. 10.1007/s00125-020-05342-x
By:
- Parkkola, Anna;
- Turtinen, Maaret;
- Härkönen, Taina;
- Ilonen, Jorma;
- Knip, Mikael;
- The Finnish Pediatric Diabetes Register;
- Groop, Per-Henrik;
- Otonkoski, Timo;
- Veijola, Riitta;
- Abram, Alar;
- Aito, Henrikka;
- Arkhipov, Ivan;
- Blanco-Sequeiros, Elina;
- Bondestam, Jonas;
- Granholm, Markus;
- Haapalehto-Ikonen, Maarit;
- Horn, Torsten;
- Huopio, Hanna;
- Janer, Joakim;
- Johansson, Christian
Publication type:
Article
Genome editing of human pancreatic beta cell models: problems, possibilities and outlook.
Published in:
Diabetologia, 2019, v. 62, n. 8, p. 1329, doi. 10.1007/s00125-019-4908-z
By:
- Balboa, Diego;
- Prasad, Rashmi B.;
- Groop, Leif;
- Otonkoski, Timo
Publication type:
Article
MANF protects human pancreatic beta cells against stress-induced cell death.
Published in:
Diabetologia, 2018, v. 61, n. 10, p. 2202, doi. 10.1007/s00125-018-4687-y
By:
- Hakonen, Elina;
- Chandra, Vikash;
- Fogarty, Christopher L.;
- Yu, Nancy Yiu-Lin;
- Ustinov, Jarkko;
- Katayama, Shintaro;
- Galli, Emilia;
- Danilova, Tatiana;
- Lindholm, Päivi;
- Vartiainen, Aki;
- Einarsdottir, Elisabet;
- Krjutškov, Kaarel;
- Kere, Juha;
- Saarma, Mart;
- Lindahl, Maria;
- Otonkoski, Timo
Publication type:
Article
In vivo activation of the PI3K-Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes.
Published in:
Diabetologia, 2014, v. 57, n. 5, p. 970, doi. 10.1007/s00125-014-3175-2
By:
- Hakonen, Elina;
- Ustinov, Jarkko;
- Eizirik, Décio;
- Sariola, Hannu;
- Miettinen, Päivi;
- Otonkoski, Timo
Publication type:
Article
sept7b is required for the differentiation of pancreatic endocrine progenitors.
Published in:
Scientific Reports, 2016, p. 24992, doi. 10.1038/srep24992
By:
- Dash, Surjya Narayan;
- Hakonen, Elina;
- Ustinov, Jarkko;
- Otonkoski, Timo;
- Andersson, Olov;
- Lehtonen, Sanna
Publication type:
Article
Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0134551
By:
- Tamminen, Kaisa;
- Balboa, Diego;
- Toivonen, Sanna;
- Pakarinen, Mikko P.;
- Wiener, Zoltan;
- Alitalo, Kari;
- Otonkoski, Timo
Publication type:
Article
Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0116668
By:
- Asikainen, Suvi;
- Heikkinen, Liisa;
- Juhila, Juuso;
- Holm, Frida;
- Weltner, Jere;
- Trokovic, Ras;
- Mikkola, Milla;
- Toivonen, Sanna;
- Balboa, Diego;
- Lampela, Riina;
- Icay, Katherine;
- Tuuri, Timo;
- Otonkoski, Timo;
- Wong, Garry;
- Hovatta, Outi
Publication type:
Article
EGFR Signaling Promotes β-Cell Proliferation and Survivin Expression during Pregnancy.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093651
By:
- Hakonen, Elina;
- Ustinov, Jarkko;
- Palgi, Jaan;
- Miettinen, Päivi J.;
- Otonkoski, Timo
Publication type:
Article
A Novel Feeder-Free Culture System for Human Pluripotent Stem Cell Culture and Induced Pluripotent Stem Cell Derivation.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076205
By:
- Vuoristo, Sanna;
- Toivonen, Sanna;
- Weltner, Jere;
- Mikkola, Milla;
- Ustinov, Jarkko;
- Trokovic, Ras;
- Palgi, Jaan;
- Lund, Riikka;
- Tuuri, Timo;
- Otonkoski, Timo
Publication type:
Article
A Defined and Xeno-Free Culture Method Enabling the Establishment of Clinical-Grade Human Embryonic, Induced Pluripotent and Adipose Stem Cells.
Published in:
PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010246
By:
- Rajala, Kristiina;
- Lindroos, Bettina;
- Hussein, Samer M.;
- Lappalainen, Riikka S.;
- Pekkanen-Mattila, Mari;
- Inzunza, Jose;
- Rozell, Björn;
- Miettinen, Susanna;
- Narkilahti, Susanna;
- Kerkelä, Erja;
- Aalto-Setälä, Katriina;
- Otonkoski, Timo;
- Suuronen, Riitta;
- Hovatta, Outi;
- Skottman, Heli
Publication type:
Article
Mechanisms of Coxsackievirus-Induced Damage to Human Pancreatic β-Cells.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 1, p. 432, doi. 10.1210/jcem.85.1.6306
By:
- ROIVAINEN, MERJA;
- RASILAINEN, SUVI;
- YLIPAASTO, PETRI;
- NISSINEN, RIIKKA;
- USTINOV, JARKKO;
- BOUWENS, LUC;
- EIZIRIK, DÉCIO L.;
- HOVI, TAPANI;
- OTONKOSKI, TIMO
Publication type:
Article
Advanced Feeder-Free Generation of Induced Pluripotent Stem Cells Directly From Blood Cells.
Published in:
Stem Cells Translational Medicine, 2014, v. 3, n. 12, p. 1402, doi. 10.5966/sctm.2014-0113
By:
- TROKOVIC, RAS;
- WELTNER, JERE;
- KEN NISHIMURA;
- MANAMI OHTAKA;
- MAHITO NAKANISHI;
- SALOMAA, VEIKKO;
- JALANKO, ANU;
- OTONKOSKI, TIMO;
- KYTTÄLÄ, AIJA
Publication type:
Article
Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08956-x
By:
- Haikala, Heidi M.;
- Anttila, Johanna M.;
- Marques, Elsa;
- Raatikainen, Tiina;
- Ilander, Mette;
- Hakanen, Henna;
- Ala-Hongisto, Hanna;
- Savelius, Mariel;
- Balboa, Diego;
- Von Eyss, Bjoern;
- Eskelinen, Vilja;
- Munne, Pauliina;
- Nieminen, Anni I.;
- Otonkoski, Timo;
- Schüler, Julia;
- Laajala, Teemu D.;
- Aittokallio, Tero;
- Sihto, Harri;
- Mattson, Johanna;
- Heikkilä, Päivi
Publication type:
Article
Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08541-2
By:
- Haikala, Heidi M.;
- Anttila, Johanna M.;
- Marques, Elsa;
- Raatikainen, Tiina;
- Ilander, Mette;
- Hakanen, Henna;
- Ala-Hongisto, Hanna;
- Savelius, Mariel;
- Balboa, Diego;
- Von Eyss, Bjoern;
- Eskelinen, Vilja;
- Munne, Pauliina;
- Nieminen, Anni I.;
- Otonkoski, Timo;
- Schüler, Julia;
- Laajala, Teemu D.;
- Aittokallio, Tero;
- Sihto, Harri;
- Mattson, Johanna;
- Heikkilä, Päivi
Publication type:
Article
Copy number variation and selection during reprogramming to pluripotency.
Published in:
Nature, 2011, v. 471, n. 7336, p. 58, doi. 10.1038/nature09871
By:
- Hussein, Samer M.;
- Batada, Nizar N.;
- Vuoristo, Sanna;
- Ching, Reagan W.;
- Autio, Reija;
- Närvä, Elisa;
- Ng, Siemon;
- Sourour, Michel;
- Hämäläinen, Riikka;
- Olsson, Cia;
- Lundin, Karolina;
- Mikkola, Milla;
- Trokovic, Ras;
- Peitz, Michael;
- Brüstle, Oliver;
- Bazett-Jones, David P.;
- Alitalo, Kari;
- Lahesmaa, Riitta;
- Nagy, Andras;
- Otonkoski, Timo
Publication type:
Article
Laminin isoforms in human embryonic stem cells: synthesis, receptor usage and growth support.
Published in:
Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 2622, doi. 10.1111/j.1582-4934.2008.00643.x
By:
- Vuoristo, Sanna;
- Virtanen, Ismo;
- Takkunen, Minna;
- Palgi, Jaan;
- Kikkawa, Yamato;
- Rousselle, Patricia;
- Sekiguchi, Kiyotoshi;
- Tuuri, Timo;
- Otonkoski, Timo
Publication type:
Article
Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.
Published in:
2002
By:
- Huopio, Hanna;
- Vauhkonen, Ilkka;
- Komulainen, Jorma;
- Niskanen, Leo;
- Otonkoski, Timo;
- Laakso, Markku
Publication type:
journal article
Carriers of an Inactivating β-Cell ATP-Sensitive Κ[sup+] Channel Mutation Have Normal Glucose Tolerance and Insulin Sensitivity and Appropriate Insulin Secretion.
Published in:
Diabetes Care, 2002, v. 25, n. 1, p. 101, doi. 10.2337/diacare.25.1.101
By:
- Huopio, Hanna;
- Vauhkonen, Ilkka;
- Niskanene, Leo;
- Laakso, Markku;
- Komulainen, Jorma;
- Otonkoski, Timo
Publication type:
Article
Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Targeting of a dCas9-Based Transcription Activator to the ORF50 Promoter.
Published in:
Viruses (1999-4915), 2020, v. 12, n. 9, p. 952, doi. 10.3390/v12090952
By:
- Elbasani, Endrit;
- Falasco, Francesca;
- Gramolelli, Silvia;
- Nurminen, Veijo;
- Günther, Thomas;
- Weltner, Jere;
- Balboa, Diego;
- Grundhoff, Adam;
- Otonkoski, Timo;
- Ojala, Päivi M.
Publication type:
Article
68Ga-NODAGA-exendin-4 PET improves the detection of focal congenital hyperinsulinism.
Published in:
Journal of Nuclear Medicine, 2021, v. 62, n. 12, p. 1, doi. 10.2967/jnumed.121.262327
By:
- Boss, Marti;
- Rottenburger, Christof;
- Brenner, Winfried;
- Blankenstein, Oliver;
- Prasad, Vikas;
- Prasad, Sonal;
- Coppi, Paolo de;
- Kühnen, Peter;
- Buitinga, Mijke;
- Nuutila, Pirjo;
- Otonkoski, Timo;
- Hussain, Khalid;
- Brom, Maarten;
- Eek, Annemarie;
- Bomanji, Jamshed;
- Shah, Pratik;
- Gotthardt, Martin
Publication type:
Article
68Ga-NODAGA-exendin-4 PET improves the detection of focal congenital hyperinsulinism.
Published in:
Journal of Nuclear Medicine, 2021, v. 62, n. 11, p. 1, doi. 10.2967/jnumed.121.262327
By:
- Boss, Marti;
- Rottenburger, Christof;
- Brenner, Winfried;
- Blankenstein, Oliver;
- Prasad, Vikas;
- Prasad, Sonal;
- de Coppi, Paolo;
- Kühnen, Peter;
- Buitinga, Mijke;
- Nuutila, Pirjo;
- Otonkoski, Timo;
- Hussain, Khalid;
- Brom, Maarten;
- Eek, Annemarie;
- Bomanji, Jamshed;
- Shah, Pratik;
- Gotthardt, Martin
Publication type:
Article
68Ga-NODAGA-exendin-4 PET improves the detection of focal congenital hyperinsulinism.
Published in:
Journal of Nuclear Medicine, 2021, v. 62, n. 10, p. 1, doi. 10.2967/jnumed.121.262327
By:
- Boss, Marti;
- Rottenburger, Christof;
- Brenner, Winfried;
- Blankenstein, Oliver;
- Prasad, Vikas;
- Prasad, Sonal;
- de Coppi, Paolo;
- Kühnen, Peter;
- Buitinga, Mijke;
- Nuutila, Pirjo;
- Otonkoski, Timo;
- Hussain, Khalid;
- Brom, Maarten;
- Eek, Annemarie;
- Bomanji, Jamshed;
- Shah, Pratik;
- Gotthardt, Martin
Publication type:
Article
68Ga-NODAGA-exendin-4 PET improves the detection of focal congenital hyperinsulinism.
Published in:
Journal of Nuclear Medicine, 2021, v. 62, n. 8, p. 1, doi. 10.2967/jnumed.121.262327
By:
- Boss, Marti;
- Rottenburger, Christof;
- Brenner, Winfried;
- Blankenstein, Oliver;
- Prasad, Vikas;
- Prasad, Sonal;
- de Coppi, Paolo;
- Kühnen, Peter;
- Buitinga, Mijke;
- Nuutila, Pirjo;
- Otonkoski, Timo;
- Hussain, Khalid;
- Brom, Maarten;
- Eek, Annemarie;
- Bomanji, Jamshed;
- Shah, Pratik;
- Gotthardt, Martin
Publication type:
Article
68Ga-NODAGA-exendin-4 PET improves the detection of focal congenital hyperinsulinism.
Published in:
Journal of Nuclear Medicine, 2021, v. 62, n. 7, p. 1, doi. 10.2967/jnumed.121.262327
By:
- Boss, Marti;
- Rottenburger, Christof;
- Brenner, Winfried;
- Blankenstein, Oliver;
- Prasad, Vikas;
- Prasad, Sonal;
- de Coppi, Paolo;
- Kühnen, Peter;
- Buitinga, Mijke;
- Nuutila, Pirjo;
- Otonkoski, Timo;
- Hussain, Khalid;
- Brom, Maarten;
- Eek, Annemarie;
- Bomanji, Jamshed;
- Shah, Pratik;
- Gotthardt, Martin
Publication type:
Article
Dedifferentiation for Replication of Human β-Cells.
Published in:
2008
By:
- Billestrup, Nils;
- Otonkoski, Timo
Publication type:
Editorial
Downregulation of EGF Receptor Signaling in Pancreatic Islets Causes Diabetes Due to Impaired Postnatal β-Cell Growth.
Published in:
Diabetes, 2006, v. 55, n. 12, p. 3299, doi. 10.2337/db06-0413
By:
- Miettinen, Päivi J.;
- Ustinov, Jarkko;
- Ormio, Päivi;
- Ru Gao;
- Palgi, Jaan;
- Hakonen, Elina;
- Juntti-Berggren, Lisa;
- Berggren, Per-Olof;
- Otonkoski, Timo
Publication type:
Article
Noninvasive Diagnosis of Focal Hyperinsulinism of Infancy With [18F]-DOPA Positron Emission Tomography.
Published in:
Diabetes, 2006, v. 55, n. 1, p. 13, doi. 10.2337/diabetes.55.01.06.db05-1128
By:
- Otonkoski, Timo;
- Näntö-Salonen, Kirsti;
- Seppänen, Marko;
- Veijola, Riitta;
- Huopio, Hanna;
- Hussain, Khalid;
- Tapanainen, Päivi;
- Eskola, Olli;
- Parkkola, Riitta;
- Ekström, Klas;
- Guiot, Yves;
- Rahier, Jacques;
- Laakso, Markku;
- Rintala, Risto;
- Nuutila, Pirjo;
- Minn, Heikki
Publication type:
Article
Lack of association of PAX4 gene with type 1 diabetes in the Finnish and Hungarian populations.
Published in:
2005
By:
- Hermann, Robert;
- Mantere, Jussi;
- Lipponen, Kati;
- Veijola, Riitta;
- Soltesz, Gyula;
- Otonkoski, Timo;
- Simell, Olli;
- Knip, Mikael;
- Ilonen, Jorma
Publication type:
journal article
Severe Persistent Hyperinsulinemic Hypoglycemia due to a De Novo Glucokinase Mutation.
Published in:
Diabetes, 2004, v. 53, n. 8, p. 2164, doi. 10.2337/diabetes.53.8.2164
By:
- Cuesta-Munoz, Antonio L.;
- Huopio, Hanna;
- Otonkoski, Timo;
- Gomez-Zumaquero, Juan M.;
- Näntö-Salonen, Kirsti;
- Rahier, Jacques;
- López-Enriquez, Soledad;
- García-Gimeno, Maria A.;
- Sanz, Pascual;
- Soriguer, Federico C.;
- Laakso, Markku
Publication type:
Article
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture.
Published in:
2003
By:
- Ru Gao;
- Gao, Ru;
- Ustinov, Jarkko;
- Pulkkinen, Mari-Anne;
- Lundin, Karolina;
- Korsgren, Olle;
- Otonkoski, Timo
Publication type:
journal article
Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release.
Published in:
2003
By:
- Otonkoski, Timo;
- Kaminen, Nina;
- Ustinov, Jarkko;
- Lapatto, Risto;
- Meissner, Thomas;
- Mayatepek, Ertan;
- Kere, Juha;
- Sipila, Ilkka;
- Sipilä, Ilkka;
- Sipilä, Ilkka
Publication type:
journal article
Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets: effects of the ob gene and compensatory growth of the implantation organ.
Published in:
2001
By:
- Tyrberg, Björn;
- Ustinov, Jarkko;
- Otonkoski, Timo;
- Andersson, Arne;
- Tyrberg, B;
- Ustinov, J;
- Otonkoski, T;
- Andersson, A
Publication type:
journal article
A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland.
Published in:
1999
By:
- Otonkoski, Timo;
- Ammala, Carina;
- Huopio, Hanna;
- Cote, Gilbert J.;
- Chapman, Joanna;
- Cosgrove, Karen;
- Ashfield, Rebecca;
- Huang, Eileen;
- Komulainen, Jorma;
- Ashcroft, Frances M.;
- Dunne, Mark J.;
- Kere, Juha;
- Thomas, Pamela M.;
- Otonkoski, T;
- Ammälä, C;
- Huopio, H;
- Cote, G J;
- Chapman, J;
- Cosgrove, K;
- Ashfield, R
Publication type:
journal article
Culture of adult human islet preparations with hepatocyte growth factor and 804G matrix is mitogenic for duct cells but not for beta-cells.
Published in:
1998
By:
- Lefebvre, Veronique H.;
- Otonkoski, Timo;
- Ustinov, Jarkko;
- Huotori, Mari-Anne;
- Pipeleers, Daniel G.;
- Bouwens, Luc;
- Lefebvre, V H;
- Otonkoski, T;
- Ustinov, J;
- Huotari, M A;
- Pipeleers, D G;
- Bouwens, L
Publication type:
journal article
Functional β-Cell Mass After Transplantation of Human Fetal Pancreatic Cells.
Published in:
Diabetes, 1997, v. 46, n. 2, p. 244, doi. 10.2337/diab.46.2.244
By:
- Beattie, Gillian M.;
- Otonkoski, Timo;
- Lopez, Ana D.;
- Hayek, Alberto
Publication type:
Article

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