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- Title
CASE REPORT: RING ENHANCING INTRACRANIAL LESION RESPONDING TO ANTITUBERCULOUS TREATMENT IN AN HIV-INFECTED PATIENT.
- Authors
Pellegrino, Daniela; Gerhardt, Juliana; Porfírio, Fátima M.V.; de Bortholi Santos, Edgar; Dauar, Rafi F.; Penalva de Oliveira, Augusto C.; Vidal, José E.
- Abstract
Cerebral tuberculomas constitute a major differential diagnosis of cerebral toxoplasmosis in human immunodeficiency virus (HIV)-infected patients in developing countries. We report the case of a 34-year old woman co-infected with HIV and possible disseminated tuberculosis (hepatitis, lymphadenopathy, and pleural effusion) who presented a large and solitary intracranial mass lesion. Despite extensive diagnostic efforts, including brain, ganglionar, and liver biopsies, no definitive diagnosis was reached. However, a trial with first-line antituberculous drugs led to a significant clinical and radiological improvement. Atypical presentations of cerebral tuberculomas should always be considered in the differential diagnosis of intracranial mass lesions in HIV-infected patients and a trial with antituberculous drugs is a valuable strategy to infer the diagnosis in a subset of patients.
- Subjects
CASE studies; HIV-positive persons; TUBERCULOSIS; TOXOPLASMOSIS; PLEURAL effusions
- Publication
Revista do Instituto de Medicina Tropical de São Paulo, 2010, Vol 52, Issue 5, p285
- ISSN
0036-4665
- Publication type
Article
- DOI
10.1590/S0036-46652010000500013