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- Title
Atelectasis caused by macrolide-resistant <i>Mycoplasma pneumoniae</i> pneumonia in an adult patient.
- Authors
Miyashita, Naoyuki; Kawai, Yasuhiro; Akaike, Hiroto; Teranishi, Hideto; Ouchi, Kazunobu; Okimoto, Niro
- Abstract
A 27-year-old, previously healthy woman was admitted to our hospital for mild pneumonia. After 2 days ceftriaxone sodium administration, her chest radiograph revealed a rightward mediastinal shift caused by atelectasis of the upper portion of the right lung. Bronchoscopic examination showed swelling in the right upper lobe bronchus and obstruction in the B 1 segmental bronchus caused by complete edematous swelling. Histopathology showed acute cellular bronchitis with edema of the bronchial wall containing lymphocytes, plasma cells, and macrophages. Mycoplasmapneumoniae was detected by culture and a polymerase chain reaction test using sputum collected during bronchoscopy, and treatment was changed to minocycline. After 7 days antibiotic therapy, her condition improved and no relapse was observed. Identification of point mutations in domain V of the 23S rRNA for macrolide-resistant M.pneumoniae was performed, and an A-to-G transition at position 2063 in domain V of the 23S rRNA gene was identified. Atelectasis caused by M. pneumoniae is thought to be a common associated finding in pediatric patients, but it is rare in adults. In addition, our patient showed extremely unusual findings with obstruction caused by complete edematous swelling.
- Subjects
ATELECTASIS; MACROLIDE antibiotics; DRUG resistance in bacteria; MYCOPLASMA pneumoniae infections; DISEASES in women; HOSPITAL admission &; discharge
- Publication
Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.), 2013, Vol 19, Issue 6, p1161
- ISSN
1341-321X
- Publication type
Article
- DOI
10.1007/s10156-013-0575-z