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- Title
Physiological carbon dioxide, bicarbonate, and pH sensing.
- Authors
Tresguerres, Martin; Buck, Jochen; Levin, Lonny R.
- Abstract
In biological systems, carbon dioxide exists in equilibrium with bicarbonate and protons. The individual components of this equilibrium (i.e., CO, HCO, and H), which must be sensed to be able to maintain cellular and organismal pH, also function as signals to modulate multiple physiological functions. Yet, the molecular sensors for CO/HCO/pH remained unknown until recently. Here, we review recent progress in delineating molecular and cellular mechanisms for sensing CO, HCO, and pH.
- Subjects
PHYSIOLOGY; CARBON dioxide; PROTONS; ORGANISMS; RESEARCH
- Publication
Pflügers Archiv: European Journal of Physiology, 2010, Vol 460, Issue 6, p953
- ISSN
0031-6768
- Publication type
Article
- DOI
10.1007/s00424-010-0865-6