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- Title
Synthesis, Redox Properties and Antibacterial Activity of Hindered Phenols Linked to Heterocycles.
- Authors
Koshelev, Vladimir N.; Primerova, Olga V.; Vorobyev, Stepan V.; Ivanova, Ludmila V.; Di Donato, Paola; Silvestri, Brigida
- Abstract
A series of benzotriazole, cyclic amides and pyrimidine derivatives, containing 2,6-di-tert-butyl-phenol fragments, were synthesized. The redox properties of obtained compounds were studied using the cyclic voltammetry on a platinum electrode in acetonitrile. The oxidation potentials of all substances were comparable to those of BHT. The obtained compounds were tested for their antibacterial activity, and N-(2-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-oxoethyl)isatin (32 μg/mL) exerted good activity against Staphylococcus aureus.
- Subjects
HETEROCYCLIC compounds; PHENOLS; PLATINUM electrodes; OXIDATION-reduction reaction; BENZOTRIAZOLE derivatives; AMIDE derivatives
- Publication
Molecules, 2020, Vol 25, Issue 10, p2370
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules25102370