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- Title
Genetic characterization of orf virus associated with an outbreak of severe orf in goats at a farm in Lusaka, Zambia (2015).
- Authors
Simulundu, Edgar; Mtine, Nandi; Kapalamula, Thoko; Kajihara, Masahiro; Qiu, Yongjin; Ngoma, James; Zulu, Victor; Kwenda, Geoffrey; Chisanga, Chrispin; Phiri, Isaac; Takada, Ayato; Mweene, Aaron
- Abstract
Orf or contagious ecthyma is a neglected and economically important zoonotic disease caused by a dermatotropic parapoxvirus that commonly affects domestic small ruminants. Although orf is globally distributed, there is a paucity of information on the disease in many African countries. Here, a suspected severe outbreak of orf in goats at a farm in Lusaka was investigated. Orf virus (ORFV) infection was confirmed by PCR amplification of viral DNA (RNA polymerase, B2L and virus interferon-resistance genes) in clinical samples. Some detected genes were sequenced and phylogenetically analyzed. This is the first report on molecular characterization of ORFV in goats in Zambia.
- Subjects
LUSAKA (Zambia); VIRAL genetics; ZOONOSES; DISEASE outbreaks; GOAT diseases; POLYMERASE chain reaction
- Publication
Archives of Virology, 2017, Vol 162, Issue 8, p2363
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-017-3352-y