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- Title
Nuclear DNA Ploidy Pattern and Tissue Levels of Dihydrophenyl-alanine and Catecholamines in Pheochromocytoma.
- Authors
Sasagawa, Isoji; Nakada, Teruhiro; Kubota, Yoko; Ishigooka, Manabu; Sawamura, Toshihiro; Suzuki, Yasuhíro
- Abstract
Flow-cytometric analysis of nuclear DNA and measurements of tissue levels of dihydroxyphenylalanine (dopa) and catecholamines were performed using fresh samples of tissue taken from 17 patients with pheochromocytoma. Nine (53%) tumors had a diploid pattern of DNA, and 8 (47%) had an aneuploid pattern. The tissue concentrations of dopa, dopamine, norepinephrine, and epinephrine did not differ significantly between pheochromocytomas with a diploid and those with an anoeuploid pattern. These results suggest that there is no correlation between nuclear DNA ploidy and tissue levels of dopa and catecholamines in pheochromocytomas. Copyright © 1995 S. Karger AG, Basel
- Publication
Urologia Internationalis, 1995, Vol 54, Issue 4, p181
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000282720