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- Title
IMMUNO-BIOCHEMICAL AND CLINICAL STUDIES ON THE EVOLUTION OF ANTIOXIDANTS' LEVEL IN THE AETIOLOGY OF PERIODONTAL DISEASE.
- Authors
Potârnichie, Oana; Nanescu, Sonia; Pasarin, Liliana; Rudnic, Ioana; Foia, Liliana; Mârtu, Silvia
- Abstract
Introduction: A comprehensive, recent analysis on the topic reached the conclusion that oxidative stress is the main cause provoking destruction of the periodontal tissue resulting from the host-microbe interaction. Purpose of the study: To investigate the correlation between periodontal health condition and the seric levels of some antioxidants. Materials and method: A representative group of 58 patients, with ages between 30 and 70 years, were examined, between 2010-2011, as to their periodontal condition, after which peripheric blood was taken over and retinol, &agr;-tocopherol, &ggr-tocopherol, &agr;-caroten, &bgr;-caroten, &bgr;-criptoxantine, zeaxantine, luteine and licopen were extracted from the serum. The values of the antioxidants were measured by high-performance chromatographic liquid technique. Results: The levels of &agr; and &bgr;-caroten, &bgr;-criptoxantine and zeaxantine were significantly lower in the patients with minimum periodonthopaty debut (p<0.001), as well as in those with increased intensity of periodontopathy debut. &bgr;-caroten and &bgr;-criptoxantine were the only antioxidants associated with a higher risk of severe periodontic pathologies. Conclusions: The low levels registered for some carotinoides, especially &bgr;-caroten and &bgr;-criptoxantine, are directly proportional with a higher prevalence of periodonthy installation.
- Subjects
OXIDATIVE stress; ANTIOXIDANTS; RISK factors of periodontal disease; LIQUID chromatography; CAROTENOIDS; VITAMIN E; VITAMIN A
- Publication
International Journal of Medical Dentistry, 2012, Vol 16, Issue 1, p52
- ISSN
2066-6063
- Publication type
Article