We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Significance of cervical gland area in predicting preterm birth for patients with threatened preterm delivery: comparison with cervical length and fetal fibronectin.
- Authors
Asakura, Hirobumi; Fukami, Takehiko; Kurashina, Ryuhei; Tateyama, Naoko; Doi, Daisuke; Takeshita, Toshiyuki
- Abstract
<bold>Background/aims: </bold>Absent cervical gland area (CGA) has been considered a predictor of preterm delivery (PTD) for women at low risk. Predictive efficacy was analyzed in women at high risk for PTD and compared with cervical length (CL) <20 mm and fetal fibronectin (fFN) in cervicovaginal secretions. <bold>Methods: </bold>Case notes were reviewed for 108 subjects with gestation of 22-33 weeks who had been admitted to hospital with threatened PTD. The uterine cervix was observed by vaginal sonography and fFN was sampled on admission. Relationships between findings and outcome of PTD at <34 weeks' gestation were analyzed. <bold>Results: </bold>Delivery at <34 weeks' gestation occurred in 14.8% of patients. Absent CGA (68.8%), short CL (75.0%), short CL without CGA (62.5%) and positive fFN (62.5%) were more frequent in these patients than in patients undelivered at <34 weeks' gestation (p < 0.05). Logistic regression analysis identified positive fFN and short CL with absent CGA as independent predictors for PTD (p < 0.0001). The mean interval from admission to delivery was 2.9 weeks in cases with fFN and both sonographic findings, compared to 9.3 weeks in cases with fFN but both sonographic finding (p = 0.0005). <bold>Conclusion: </bold>Short CL with absent CGA represents an independent predictor for PTD, as does fFN.
- Subjects
PREGNANCY; REGRESSION analysis; PREMATURE infants; PREMATURE labor; FIBRONECTINS
- Publication
Gynecologic & Obstetric Investigation, 2009, Vol 68, Issue 1, p1
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000209394