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- Title
High-density genome-wide association mapping implicates an F-box encoding gene in Medicago truncatula resistance to Aphanomyces euteiches.
- Authors
Bonhomme, Maxime; André, Olivier; Badis, Yacine; Ronfort, Joëlle; Burgarella, Concetta; Chantret, Nathalie; Prosperi, Jean‐Marie; Briskine, Roman; Mudge, Joann; Debéllé, Frédéric; Navier, Hélène; Miteul, Henri; Hajri, Ahmed; Baranger, Alain; Tiffin, Peter; Dumas, Bernard; Pilet‐Nayel, Marie‐Laure; Young, Nevin D.; Jacquet, Christophe
- Abstract
The use of quantitative disease resistance ( QDR) is a promising strategy for promoting durable resistance to plant pathogens, but genes involved in QDR are largely unknown. To identify genetic components and accelerate improvement of QDR in legumes to the root pathogen Aphanomyces euteiches, we took advantage of both the recently generated massive genomic data for Medicago truncatula and natural variation of this model legume., A high-density (≈5.1 million single nucleotide polymorphisms ( SNPs)) genome-wide association study ( GWAS) was performed with both in vitro and glasshouse phenotyping data collected for 179 lines., GWAS identified several candidate genes and pinpointed two independent major loci on the top of chromosome 3 that were detected in both phenotyping methods. Candidate SNPs in the most significant locus (
- Subjects
GENETIC code; APHANOMYCES euteiches; PHYTOPATHOGENIC microorganisms; MEDICAGO truncatula; SINGLE nucleotide polymorphisms; OOMYCETES
- Publication
New Phytologist, 2014, Vol 201, Issue 4, p1328
- ISSN
0028-646X
- Publication type
Article
- DOI
10.1111/nph.12611