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- Title
Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008-2012.
- Authors
Chau-Ting Yeh; Kung-Hao Liang; Ming-Ling Chang; Chao-Wei Hsu; Yi-Cheng Chen; Chih-Lang Lin; Wey-Ran Lin; Ming-Wei Lai; Yeh, Chau-Ting; Liang, Kung-Hao; Chang, Ming-Ling; Hsu, Chao-Wei; Chen, Yi-Cheng; Lin, Chih-Lang; Lin, Wey-Ran; Lai, Ming-Wei
- Abstract
We examined the characteristic changes of hepatitis B virus (HBV) in antiviral drug treatment-naive patients referred for pretreatment evaluation in Taiwan during 2008-2012. Over time, we observed substantial decreases in the prevalence of HBV e antigen (HBeAg) and increasing prevalence of the precore G1899A mutation and HBV-DNA levels in HBeAg-positive patients.
- Subjects
TAIWAN; HEPATITIS B treatment; ANTIVIRAL agents; PHENOTYPES; GENOTYPES; VIRAL mutation; HEPATITIS associated antigen; PUBLIC health
- Publication
Emerging Infectious Diseases, 2017, Vol 23, Issue 5, p820
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2305.161894