We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Expansion of Shiga Toxin-Producing Escherichia coli by Use of Bovine Antibiotic Growth Promoters.
- Authors
Jong-Chul Kim; Linda Chui; Yang Wang; Jianzhong Shen; Byeonghwa Jeon; Kim, Jong-Chul; Chui, Linda; Wang, Yang; Shen, Jianzhong; Jeon, Byeonghwa
- Abstract
Antibiotics are routinely used in food-producing animals to promote growth and prevent infectious diseases. We investigated the effects of bovine antibiotic growth promoters (bAGPs) on the propagation and spread of Shiga toxin (Stx)-encoding phages in Escherichia coli. Co-culture of E. coli O157:H7 and other E. coli isolated from cattle in the presence of sublethal concentrations of bAGPs significantly increased the emergence of non-O157, Stx-producing E. coli by triggering the SOS response system in E. coli O157:H7. The most substantial mediation of Stx phage transmission was induced by oxytetracyline and chlortetracycline, which are commonly used in agriculture. bAGPs may therefore contribute to the expansion of pathogenic Stx-producing E. coli.
- Subjects
ANTIBIOTICS in animal nutrition; ENTEROTOXINS; ESCHERICHIA coli; ESCHERICHIA coli diseases; BACTERIOPHAGES; OXYTETRACYCLINE; CATTLE
- Publication
Emerging Infectious Diseases, 2016, Vol 22, Issue 5, p802
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2205.151584