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- Title
Cancer Gene Therapy: The power of negative thinking.
- Authors
Lotze, M. T.
- Abstract
The article discusses the pathways for the gene therapy of cancer. The first pathway in gene therapy was discussed. The use of genetic constructs to confer novel properties of the cell, the second pathway, was described. The third pathway is to use nominally tumor-selective viruses that mediate oncolytic effects of the tumor. A fourth nascent pathway focuses on strategies designed to modify the biology of the tumor-reactive inflammatory cells.
- Subjects
CANCER treatment; GENE therapy; THERAPEUTICS; TUMORS; VIRUSES
- Publication
Gene Therapy, 2006, Vol 13, Issue 3, p191
- ISSN
0969-7128
- Publication type
Article
- DOI
10.1038/sj.gt.3302633