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- Title
CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis.
- Authors
Romme Christensen, Jeppe; Börnsen, Lars; Khademi, Mohsen; Olsson, Tomas; Jensen, Poul Erik; Sørensen, Per Soelberg; Sellebjerg, Finn
- Abstract
The article presents a study which investigates the relationship between cerebrospinal fluid (CSF) inflammation, axonal damage, and progressive multiple sclerosis (MS). Enzyme-linked immunosorbent assay (ELISA) was used to analysed CSF samples which was obtained from the subjected MS patients. Results confirmed that there is an increase in inflammation biomarkers in progressive MS patients, therefore, a close relationship between CSF inflammation, axonal damage, and demyelination was revealed.
- Subjects
MULTIPLE sclerosis research; CEREBROSPINAL fluid examination; ENZYME-linked immunosorbent assay; BIOMARKERS; AXONS; DEMYELINATION; DISEASES
- Publication
Multiple Sclerosis Journal, 2013, Vol 19, Issue 7, p877
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458512466929