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- Title
Measuring the Plasmodium falciparum HRP2 protein in blood from artesunate-treated malaria patients predicts post-artesunate delayed hemolysis.
- Authors
Ndour, Papa Alioune; Larréché, Sébastien; Mouri, Oussama; Argy, Nicolas; Gay, Frédérick; Roussel, Camille; Jauréguiberry, Stéphane; Perillaud, Claire; Langui, Dominique; Biligui, Sylvestre; Chartrel, Nathalie; Mérens, Audrey; Kendjo, Eric; Ghose, Aniruddha; Hassan, Md. Mahtab Uddin; Hossain, Md. Amir; Kingston, Hugh W. F.; Plewes, Katherine; Dondorp, Arjen M.; Danis, Martin
- Abstract
The article discusses the risk of developing post-artesunate delayed hemolysis (PADH) among patients who received artesunate drug, as treatment for malaria. It mentions the use of an optimizedmembrane permeabilization method for determining the risk of PADH among artesunate-treated malaria patients. It also notes on the development of a semiquantitative titration method for early diagnosis.
- Subjects
DRUG side effects; HEMOLYSIS &; hemolysins; MALARIA treatment; ARTEMISININ; ANTIMALARIALS
- Publication
Science Translational Medicine, 2017, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aaf9377