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- Title
Response of Meningeal Carcinomatosis from Breast Cancer to Capecitabine Monotherapy: A Case Report.
- Authors
Tanaka, Yumi; Oura, Shoji; Yoshimasu, Tatsuya; Ohta, Fuminori; Naito, Koma; Nakamura, Rie; Hirai, Yoshimitsu; Ikeda, Masako; Okamura, Yoshitaka
- Abstract
A 62-year-old woman with breast cancer received neoadjuvant chemotherapy followed by breast-conserving surgery and sentinel node biopsy. During adjuvant endocrine therapy with aromatase inhibitor, she developed multiple bone metastases. Thereafter, she received tamoxifen and zoledronate therapy. In May 2011, she developed a tongue deviation and was diagnosed as having meningeal carcinomatosis. The tongue deviation disappeared 3 weeks after taking capecitabine (2,400 mg/day). Magnetic resonance imaging of the brain showed regression of meningeal carcinomatosis. Levels of tumor markers CEA and CA15-3 changed from 96.0 IU/ml and 3.5 ng/ml to 47.0 IU/ml and 1.5 ng/ml, respectively. Progression-free survival with capecitabine monotherapy was 5 months. Copyright © 2013 S. Karger AG, Basel
- Publication
Case Reports in Oncology, 2013, Vol 6, Issue 1, p1
- ISSN
1662-6575
- Publication type
Article
- DOI
10.1159/000345097