We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Mouse model of DNCB-induced atopic dermatitis.
- Authors
Hamad, Alshammari Fanar; Jong-Hun Han; Rather, Irfan A.
- Abstract
Atopic dermatitis is a skin disease characterized by allergic skin inflammation, redness and itching. The animal model is necessary to find out new drugs. The DNCB-induced animal model of atopic dermatitis includes the following steps: 1) Selection of animals; 2) Shaving of dorsal skin; 3) Applying DNCB once in 24 hours for three days; 4) Monitoring the development of atopy on day 4 post DNCB application. Further, the efficacy of reference drug can be determined by applying on the atopy skin, depends on the nature and aim of the work.
- Subjects
ANIMAL models in research; SKIN diseases; INFLAMMATION; DRUG development; ATOPIC dermatitis
- Publication
Bangladesh Journal of Pharmacology, 2017, Vol 12, Issue 2, p147
- ISSN
1991-007X
- Publication type
Article
- DOI
10.3329/bjp.v12i2.31950