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Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97197-4
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- Article
ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis.
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- Cellular Microbiology, 2017, v. 19, n. 7, p. n/a, doi. 10.1111/cmi.12726
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- Article
Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host-pathogen interactions.
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- Cellular Microbiology, 2014, v. 16, n. 2, p. 195, doi. 10.1111/cmi.12214
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- Article
In vivo imaging of MmpL transporters reveals distinct subcellular locations for export of mycolic acids and non-essential trehalose polyphleates in the mycobacterial outer membrane.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-34315-4
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- Article
Playing hide-and-seek with host macrophages through the use of mycobacterial cell envelope phthiocerol dimycocerosates and phenolic glycolipids.
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- Frontiers in Cellular & Infection Microbiology, 2014, p. 1, doi. 10.3389/fcimb.2014.00173
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- Article
Les bacilles de la tuberculose bovine: Une évolution aux dépens de la transmissibilité chez l'homme.
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- Médecine Sciences, 2015, v. 31, n. 2, p. 123, doi. 10.1051/medsci/20153102003
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- Article
Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis.
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- BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01337-9
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- Article
Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages.
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- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00002
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- Article
Phospholipases C are involved in the virulence of Mycobacterium tuberculosis.
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- Molecular Microbiology, 2002, v. 45, n. 1, p. 203, doi. 10.1046/j.1365-2958.2002.03009.x
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- Article
Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis.
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- Molecular Microbiology, 2002, v. 44, n. 4, p. 1109, doi. 10.1046/j.1365-2958.2002.02953.x
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- Article
An essential role for phoP in Mycobacterium tuberculosis virulence.
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- Molecular Microbiology, 2001, v. 41, n. 1, p. 179, doi. 10.1046/j.1365-2958.2001.02500.x
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- Article
Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis.
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- Molecular Microbiology, 1999, v. 34, n. 2, p. 257, doi. 10.1046/j.1365-2958.1999.01593.x
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- Article
Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope.
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- Molecular Microbiology, 1999, v. 31, n. 5, p. 1573, doi. 10.1046/j.1365-2958.1999.01310.x
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- Article
Functional Characterisation of Three <i>O</i>-methyltransferases Involved in the Biosynthesis of Phenolglycolipids in <i>Mycobacterium tuberculosis</i>.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058954
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Mycobacterium tuberculosis Lineage Influences Innate Immune Response and Virulence and Is Associated with Distinct Cell Envelope Lipid Profiles.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0023870
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- Article
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages.
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- PLoS Pathogens, 2021, v. 17, n. 11, p. 1, doi. 10.1371/journal.ppat.1010020
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De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis.
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- eLife, 2022, p. 1, doi. 10.7554/eLife.71946
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- Article
CR3 Engaged by PGL-I Triggers Syk-Calcineurin-NFATc to Rewire the Innate Immune Response in Leprosy.
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- Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02913
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- Article
Mycobacteria–host interactions in human bronchiolar airway organoids.
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- Molecular Microbiology, 2022, v. 117, n. 3, p. 682, doi. 10.1111/mmi.14824
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- Article
Conformational flexibility of coenzyme A and its impact on the post‐translational modification of acyl carrier proteins by 4′‐phosphopantetheinyl transferases.
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- FEBS Journal, 2020, v. 287, n. 21, p. 4729, doi. 10.1111/febs.15273
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- Article
PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves.
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- PLoS Pathogens, 2018, p. 1, doi. 10.1371/journal.ppat.1007151
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Identification of genetic loci implicated in the survival of Mycobacterium smegmatis in human mononuclear phagocytes.
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- Molecular Microbiology, 1998, v. 29, n. 2, p. 465, doi. 10.1046/j.1365-2958.1998.00933.x
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- Article
Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis.
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- FEBS Journal, 2010, v. 277, n. 12, p. 2715, doi. 10.1111/j.1742-464X.2010.07688.x
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Molecular dissection of the biosynthetic relationship between phthiocerol and phthiodiolone dimycocerosates and their critical role in the virulence and permeability of Mycobacterium tuberculosis.
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- FEBS Journal, 2007, v. 274, n. 8, p. 1957, doi. 10.1111/j.1742-4658.2007.05740.x
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The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in <i>Mycobacterium tuberculosis</i>.
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- PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004183
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4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo.
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- PLoS Pathogens, 2012, v. 8, n. 12, p. 1, doi. 10.1371/journal.ppat.1003097
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Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids.
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- PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000289
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The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages.
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- Cells (2073-4409), 2020, v. 9, n. 3, p. 666, doi. 10.3390/cells9030666
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Mycobacterium tuberculosis and M. bovis BCG Moreau Fumarate Reductase Operons Produce Different Polypeptides That May Be Related to Non-canonical Functions.
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- Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.624121
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- Article
Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors.
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- Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. N.PAG, doi. 10.3389/fcimb.2020.00420
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- Article
Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids.
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- PLoS Pathogens, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.ppat.1011559
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Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli.
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- PLoS Pathogens, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.ppat.1011437
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- Article