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- Title
Breaching the great wall: peptidoglycan and microbial interactions.
- Authors
Cloud-Hansen, Karen A.; Peterson, S. Brook; Stabb, Eric V.; Goldman, William E.; McFall-Ngai, Margaret J.; Handelsman, Jo
- Abstract
Once thought to be a process that occurred only in a few human pathogens, release of biologically active peptidoglycan fragments during growth by Gram-negative bacteria controls many types of bacterial interaction, including symbioses and interactions between microorganisms. This Perspective explores the role of peptidoglycan fragments in mediating a range of microbial–host interactions, and discusses the many systems in which peptidoglycan fragments released during bacterial growth might be active.
- Subjects
PEPTIDOGLYCANS; BACTERIAL cell walls; MICROBIAL polysaccharides; PEPTIDES; GLUTAMIC acid; GLYCOSYLTRANSFERASES; CARBOXYPEPTIDASES
- Publication
Nature Reviews Microbiology, 2006, Vol 4, Issue 9, p710
- ISSN
1740-1526
- Publication type
Article
- DOI
10.1038/nrmicro1486