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- Title
Holmes' tremor caused by coexisting Parkinson's disease in a case of spinocerebellar ataxia type 31.
- Authors
Shimizu, Kazutaka; Hanajima, Ritsuko; Satou, Sumito; Shimizu, Takahiro; Watanabe, Katsushige; Kaneko, Atsushi; Iizuka, Takahiro; Nishiyama, Kazutoshi
- Abstract
Holmes' tremor is a low-frequency resting and intention tremor. Here, we report a case of spinocerebellar ataxia type 31 with an unusual presentation of Holmes' tremor. We traced it to the development of Parkinson's disease in the patient. L-dopa was insufficient for tremor, but zonisamide and ventralis intermedius thalamotomy were effective. Both cerebellar and dopaminergic system damage are thus required to express Holmes' tremor.
- Subjects
SPINOCEREBELLAR ataxia; PARKINSON'S disease; THALAMOTOMY; DOPA; TREMOR
- Publication
Neurology & Clinical Neuroscience, 2017, Vol 5, Issue 2, p71
- ISSN
2049-4173
- Publication type
Article
- DOI
10.1111/ncn3.12114