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- Title
Memenin Nadir Görülen Benign Proliferatif Lezyonu: Psödoanjiyomatöz Stromal Hiperplazi (PASH).
- Authors
Akýn, Murat; Karabacak, Harun; Yilmaz, Guldal; Yavuz, Aydin; Nasirov, Mahir; Kurukahvecioğlu, Osman
- Abstract
Objective: Pseudoangiomatous stromal hyperplasia (PASH), a benign proliferative lesion of breast stroma, is a mass lesion including anastomosing clefts reminiscent of blood vessels. It is still having an indefinite etiology and pathogenesis, and thought to represent a neoplastic process of myofibroblastical cell origin. The objective of this study is to evaluate the clinical and histopathological features and surgical indications of the patients diagnosed as PASH. Materials and methods: Five patients, attending to Gazi University Medical Faculty Hospital and diagnosed pathologically as PASH were examined retrospectively. The patients were re-evaluated by data concerning their age, complaints, family history, radiological findings and diagnostic methods. Results: Four patients have been presented with complaints of enlarging breast mass while the other with haemorrhagic nipple discharge. Ages ranged from 25 to 50 with the meanage of 35. Pathologic diagnosis was made by the examination of core biopsy in 1 case, ultrasound-guided core biopsy in 2 cases, stereotactic-guided excisional biopsy in 1 case, and wide excisional biopsy in 1 case. Conclusion: PASH, even though being benign and encountered rarely, must absolutely be taken into account in the differential diagnosis of patients with a breast mass detected radiologically or clinically. Histopathological diagnosis must be supported by immunohistochemical staining.
- Publication
Gazi Medical Journal, 2017, Vol 8, Issue 2, p90
- ISSN
1300-056X
- Publication type
Article
- DOI
10.12996/gmj.2017.26