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- Title
Synthesis and Cytotoxicity of Dendritic Platinum Nanoparticles with HEK-293 Cells.
- Authors
Shim, Kyubin; Kim, Jeonghun; Heo, Yoon ‐ Uk; Jiang, Bo; Li, Cuiling; Shahabuddin, Mohammed; Wu, Kevin C. ‐ W.; Hossain, Md. Shahriar A.; Yamauchi, Yusuke; Kim, Jung Ho
- Abstract
Dendritic platinum nanoparticles (DPNs) have been synthesized from l-ascorbic acid and an amphiphilic non-ionic surfactant (Brij-58) via a sonochemical method. The particle size and shape of the DPNs could be tuned by changing the reduction temperature, resulting in a uniform DPN with a size of 23 nm or 60 nm. The facets of DPNs have been studied by high-resolution transmission electron microscopy. The cytotoxicity of DPNs has been investigated using human embryonic kidney cells (HEK-293), and the biological adaptability exhibited by DPNs has opened a pathway to biomedical applications such as drug-delivery systems, photothermal treatment, and biosensors.
- Subjects
PLATINUM; NANOPARTICLES; VITAMIN C; SURFACE active agents; TRANSMISSION electron microscopy
- Publication
Chemistry - An Asian Journal, 2017, Vol 12, Issue 1, p21
- ISSN
1861-4728
- Publication type
Article
- DOI
10.1002/asia.201601239