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Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.
Published in:
EMBO Molecular Medicine, 2015, v. 7, n. 12, p. 1529, doi. 10.15252/emmm.201505439
By:
- Fernández‐Santiago, Rubén;
- Carballo‐Carbajal, Iria;
- Castellano, Giancarlo;
- Torrent, Roger;
- Richaud, Yvonne;
- Sánchez‐Danés, Adriana;
- Vilarrasa‐Blasi, Roser;
- Sánchez‐Pla, Alex;
- Mosquera, José Luis;
- Soriano, Jordi;
- López‐Barneo, José;
- Canals, Josep M;
- Alberch, Jordi;
- Raya, Ángel;
- Vila, Miquel;
- Consiglio, Antonella;
- Martín‐Subero, José I;
- Ezquerra, Mario;
- Tolosa, Eduardo
Publication type:
Article
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.
Published in:
EMBO Molecular Medicine, 2012, v. 4, n. 5, p. 380, doi. 10.1002/emmm.201200215
By:
- Sánchez-Danés, Adriana;
- Richaud-Patin, Yvonne;
- Carballo-Carbajal, Iria;
- Jiménez-Delgado, Senda;
- Caig, Carles;
- Mora, Sergio;
- Di Guglielmo, Claudia;
- Ezquerra, Mario;
- Patel, Bindiben;
- Giralt, Albert;
- Canals, Josep M.;
- Memo, Maurizio;
- Alberch, Jordi;
- López-Barneo, José;
- Vila, Miquel;
- Cuervo, Ana Maria;
- Tolosa, Eduard;
- Consiglio, Antonella;
- Raya, Angel
Publication type:
Article
Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes.
Published in:
Nature Biotechnology, 1999, v. 17, n. 7, p. 653, doi. 10.1038/10862
By:
- Wagner, Joseph;
- Åkerud, Peter;
- Castro, Diogo S.;
- Holm, Pontus C.;
- Canals, Josep M.;
- Snyder, Evan Y.;
- Perlmann, Thomas;
- Arenas, Ernest
Publication type:
Article
Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder.
Published in:
2022
By:
- Rosser, Anne E.;
- Busse, Monica E.;
- Gray, William P.;
- Badin, Romina Aron;
- Perrier, Anselme L.;
- Wheelock, Vicki;
- Cozzi, Emanuele;
- Martin, Unai Perpiña;
- Salado-Manzano, Cristina;
- Mills, Laura J.;
- Drew, Cheney;
- Goldman, Steven A.;
- Canals, Josep M.;
- Thompson, Leslie M.
Publication type:
journal article
Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor.
Published in:
Nature Medicine, 1999, v. 5, n. 10, p. 1188, doi. 10.1038/13514
By:
- Naveilhan, Philippe;
- Hassani, Hessameh;
- Canals, Josep M.;
- Ekstrand, A. Jonas;
- Larefalk, Åsa;
- Chhajlani, Vijay;
- Arenas, Ernest;
- Gedda, Karin;
- Svensson, Lennart;
- Thoren, Peter;
- Ernfors, Patrik
Publication type:
Article
Brain-Derived Neurotrophic Factor Regulates the Onset and Severity of Motor Dysfunction Associated with Enkephalinergic Neuronal Degeneration in Huntington's Disease.
Published in:
Journal of Neuroscience, 2004, v. 24, n. 35, p. 7727, doi. 10.1523/JNEUROSCI.1197-04.2004
By:
- Canals, Josep M.;
- Pineda, José R.;
- Torres-Peraza, Jesús F.;
- Bosch, Miquel;
- Martín-Ibañez, Raquel;
- Muñoz, M. Teresa;
- Mengod, Guadalupe;
- Ernfors, Patrik;
- Alberch, Jordi
Publication type:
Article
Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.
Published in:
2006
By:
- Borrell-Pagès, Maria;
- Canals, Josep M.;
- Cordelières, Fabrice P.;
- Parker, J. Alex;
- Pineda, José R.;
- Grange, Ghislaine;
- Bryson, Elzbieta A.;
- Guillermier, Martine;
- Hirsch, Etienne;
- Hantraye, Philippe;
- Cheetham, Michael E.;
- Néri, Christian;
- Alberch, Jordi;
- Brouillet, Emmanuel;
- Saudou, Frédéric;
- Humbert, Sandrine;
- Borrell-Pagès, Maria;
- Cordelières, Fabrice P;
- Pineda, José R;
- Néri, Christian
Publication type:
journal article
Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 49, p. 12748, doi. 10.1523/JNEUROSCI.3873-06.2006
By:
- Del Toro, Daniel;
- Canals, Josep M.;
- Ginés, Silvia;
- Kojima, Masami;
- Egea, Gustavo;
- Alberch, Jordi
Publication type:
Article
Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons.
Published in:
Pflügers Archiv: European Journal of Physiology, 2018, v. 470, n. 9, p. 1359, doi. 10.1007/s00424-018-2155-7
By:
- Telezhkin, Vsevolod;
- Straccia, Marco;
- Yarova, Polina;
- Pardo, Monica;
- Yung, Sun;
- Vinh, Ngoc-Nga;
- Hancock, Jane M.;
- Barriga, Gerardo Garcia-Diaz;
- Brown, David A.;
- Rosser, Anne E.;
- Brown, Jonathan T.;
- Canals, Josep M.;
- Randall, Andrew D.;
- Allen, Nicholas D.;
- Kemp, Paul J.
Publication type:
Article
Cell Banking of HEK293T cell line for clinical-grade lentiviral particles manufacturing.
Published in:
Translational Medicine Communications, 2020, v. 5, n. 1, p. 1, doi. 10.1186/s41231-020-00075-w
By:
- Perpiñá, Unai;
- Herranz, Cristina;
- Martín-Ibáñez, Raquel;
- Boronat, Anna;
- Chiappe, Felipe;
- Monforte, Verónica;
- Orpella-Aceret, Gemma;
- González, Ester;
- Olivé, Myriam;
- Castella, María;
- Suñé, Guillermo;
- Urbano-Ispizua, Álvaro;
- Delgado, Julio;
- Juan, Manel;
- Canals, Josep M.
Publication type:
Article
CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease.
Published in:
PLoS ONE, 2019, v. 14, n. 12, p. 1, doi. 10.1371/journal.pone.0224901
By:
- Comella Bolla, Andrea;
- Valente, Tony;
- Miguez, Andres;
- Brito, Veronica;
- Gines, Silvia;
- Solà, Carme;
- Straccia, Marco;
- Canals, Josep M.
Publication type:
Article
Soluble mutant huntingtin drives early human pathogenesis in Huntington’s disease.
Published in:
Cellular & Molecular Life Sciences, 2023, v. 80, n. 8, p. 1, doi. 10.1007/s00018-023-04882-w
By:
- Miguez, Andrés;
- Gomis, Cinta;
- Vila, Cristina;
- Monguió-Tortajada, Marta;
- Fernández-García, Sara;
- Bombau, Georgina;
- Galofré, Mireia;
- García-Bravo, María;
- Sanders, Phil;
- Fernández-Medina, Helena;
- Poquet, Blanca;
- Salado-Manzano, Cristina;
- Roura, Santiago;
- Alberch, Jordi;
- Segovia, José Carlos;
- Allen, Nicholas D.;
- Borràs, Francesc E.;
- Canals, Josep M.
Publication type:
Article
Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus.
Published in:
Brain: A Journal of Neurology, 2013, v. 136, n. 4, p. 1161, doi. 10.1093/brain/awt044
By:
- Torres-Peraza, Jesús F.;
- Engel, Tobias;
- Martín-Ibáñez, Raquel;
- Sanz-Rodríguez, Amaya;
- Fernández-Fernández, M. Rosario;
- Esgleas, Miriam;
- Canals, Josep M.;
- Henshall, David C.;
- Lucas, José J.
Publication type:
Article
Altered P2X<sub>7</sub>-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration.
Published in:
FASEB Journal, 2009, v. 23, n. 6, p. 1893, doi. 10.1096/fj.08-122275
By:
- Díaz-Hernández, Miguel;
- Díez-Zaera, María;
- Sánchez-Nogueiro, Jesús;
- Gómez-Villafuertes, Rosa;
- Canals, Josep M.;
- Albercht, Jordi;
- Miras-Portugal, María Teresa;
- Lucas, José J.
Publication type:
Article
Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease.
Published in:
Journal of Neurochemistry, 2010, v. 115, n. 1, p. 153, doi. 10.1111/j.1471-4159.2010.06912.x
By:
- del Toro, Daniel;
- Xifr, Xavier;
- Pol, Albert;
- Humbert, Sandrine;
- Saudou, Frédéric;
- Canals, Josep M.;
- Alberch, Jordi
Publication type:
Article
Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington’s disease by preventing p75<sup>NTR</sup> up-regulation and astrocyte-mediated inflammation.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 17, p. 4958, doi. 10.1093/hmg/ddv218
By:
- Miguez, Andrés;
- Barriga, Gerardo García-Díaz;
- Brito, Verónica;
- Straccia, Marco;
- Giralt, Albert;
- Ginés, Silvia;
- Canals, Josep M.;
- Alberch, Jordi
Publication type:
Article
A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.
Published in:
Human Molecular Genetics, 2013, v. 22, n. 19, p. 3869, doi. 10.1093/hmg/ddt242
By:
- Damiano, Maria;
- Diguet, Elsa;
- Malgorn, Carole;
- D'Aurelio, Marilena;
- Galvan, Laurie;
- Petit, Fanny;
- Benhaim, Lucile;
- Guillermier, Martine;
- Houitte, Diane;
- Dufour, Noelle;
- Hantraye, Philippe;
- Canals, Josep M.;
- Alberch, Jordi;
- Delzescaux, Thierry;
- Déglon, Nicole;
- Beal, M. Flint;
- Brouillet, Emmanuel
Publication type:
Article
Neuropeptide Y alters sedation through a hypothalamic Y[sub 1]-mediated mechanism.
Published in:
European Journal of Neuroscience, 2001, v. 13, n. 12, p. 2241, doi. 10.1046/j.0953-816x.2001.01601.x
By:
- Naveilhan, Philippe;
- Canals, Josep M.;
- Valjakka, Antti;
- Vartiainen, Jukka;
- Arenas, Ernest;
- Ernfors, Patrik
Publication type:
Article
Cell Therapy for Huntington's Disease: Learning from Failure.
Published in:
2021
By:
- Rosser, Anne E.;
- Busse, Monica;
- Aron Badin, Romina;
- Canals, Josep M.;
- Wheelock, Vicki;
- Perrier, Anselme L.;
- Gray, William;
- Thompson, Leslie;
- Goldman, Steven
Publication type:
Letter
Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in hPSCs.
Published in:
Cells (2073-4409), 2022, v. 11, n. 13, p. N.PAG, doi. 10.3390/cells11131984
By:
- Molina-Ruiz, Francisco J.;
- Introna, Clelia;
- Bombau, Georgina;
- Galofre, Mireia;
- Canals, Josep M.
Publication type:
Article
Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra.
Published in:
European Journal of Neuroscience, 2006, v. 23, n. 4, p. 1063, doi. 10.1111/j.1460-9568.2006.04601.x
By:
- Martín‐Ibañez, Raquel;
- Jenstad, Monica;
- Berghuis, Paul;
- Edwards, Robert H.;
- Hioki, Hiroyuki;
- Kaneko, Takeshi;
- Mulder, Jan;
- Canals, Josep M.;
- Ernfors, Patrik;
- Chaudhry, Farrukh A.;
- Harkany, Tibor
Publication type:
Article
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain.
Published in:
European Journal of Neuroscience, 2006, v. 23, n. 3, p. 649, doi. 10.1111/j.1460-9568.2006.04590.x
By:
- Ginés, Silvia;
- Bosch, Miquel;
- Marco, Sonia;
- Gavaldà, Núria;
- Díaz‐Hernández, Miguel;
- Lucas, José J.;
- Canals, Josep M.;
- Alberch, Jordi
Publication type:
Article
Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis.
Published in:
2017
By:
- Pulido-Salgado, Marta;
- Vidal-Taboada, Jose M.;
- Diaz-Barriga, Gerardo Garcia;
- Serratosa, Joan;
- Valente, Tony;
- Castillo, Paola;
- Matalonga, Jonathan;
- Straccia, Marco;
- Canals, Josep M.;
- Valledor, Annabel;
- Solà, Carme;
- Saura, Josep;
- Garcia Diaz-Barriga, Gerardo
Publication type:
journal article
Human embryonic mesenchymal lung-conditioned medium promotes differentiation to myofibroblast and loss of stemness phenotype in lung adenocarcinoma cell lines.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-021-02206-z
By:
- Canals, Jordi;
- Navarro, Alfons;
- Vila, Cristina;
- Canals, Josep M.;
- Díaz, Tania;
- Acosta-Plasencia, Melissa;
- Cros-Font, Coralí;
- Han, Bing;
- He, Yangyi;
- Monzó, Mariano
Publication type:
Article
Is the Immunological Response a Bottleneck for Cell Therapy in Neurodegenerative Diseases?
Published in:
Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.00250
By:
- Salado-Manzano, Cristina;
- Perpiña, Unai;
- Straccia, Marco;
- Molina-Ruiz, Francisco J.;
- Cozzi, Emanuele;
- Rosser, Anne E.;
- Canals, Josep M.
Publication type:
Article
Reduced Fractalkine Levels Lead to Striatal Synaptic Plasticity Deficits in Huntington's Disease.
Published in:
Frontiers in Cellular Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fncel.2020.00163
By:
- Kim, Anya;
- García-García, Esther;
- Straccia, Marco;
- Comella-Bolla, Andrea;
- Miguez, Andrés;
- Masana, Mercè;
- Alberch, Jordi;
- Canals, Josep M.;
- Rodríguez, Manuel J.
Publication type:
Article
Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1.
Published in:
Frontiers in Cellular Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fncel.2020.00093
By:
- Sancho-Balsells, Anna;
- Brito, Veronica;
- Fernández, Belissa;
- Pardo, Mónica;
- Straccia, Marco;
- Ginés, Silvia;
- Alberch, Jordi;
- Hernández, Isabel;
- Arranz, Belén;
- Canals, Josep M.;
- Giralt, Albert
Publication type:
Article
Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling.
Published in:
Neural Development, 2010, v. 5, p. 21, doi. 10.1186/1749-8104-5-21
By:
- Urbán, Noelia;
- Martín-Ibáñez, Raquel;
- Herranz, Cristina;
- Esgleas, Miriam;
- Crespo, Empar;
- Pardo, Monica;
- Crespo-Enríquez, Ivan;
- Méndez-Gómez, Héctor R;
- Waclaw, Ronald;
- Chatzi, Christina;
- Álvarez, Susana;
- Álvarez, Rosana;
- Duester, Gregg;
- Campbell, Kenneth;
- de Lera, Angel R.;
- Vicario-Abejón, Carlos;
- Martinez, Salvador;
- Alberch, Jordi;
- Canals, Josep M.
Publication type:
Article
Brain-derived neurotrophic factor modulates dopaminergic de?cits in a transgenic mouse model of Huntington’s disease.
Published in:
Journal of Neurochemistry, 2005, v. 93, n. 5, p. 1057, doi. 10.1111/j.1471-4159.2005.03047.x
By:
- x00E9; R.#Pineda, Jos&;
- Canals, Josep M;
- Bosch, Miquel;
- Adell, Albert;
- Mengod, Guadalupe;
- Artigas, Francesc;
- Ernfors, Patrik;
- Alberch, Jordi
Publication type:
Article
Tbr1 Misexpression Alters Neuronal Development in the Cerebral Cortex.
Published in:
Molecular Neurobiology, 2022, v. 59, n. 9, p. 5750, doi. 10.1007/s12035-022-02936-x
By:
- Crespo, Inmaculada;
- Pignatelli, Jaime;
- Kinare, Veena;
- Méndez-Gómez, Héctor R.;
- Esgleas, Miriam;
- Román, María José;
- Canals, Josep M.;
- Tole, Shubha;
- Vicario, Carlos
Publication type:
Article
Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation.
Published in:
Molecular Neurobiology, 2020, v. 57, n. 6, p. 2766, doi. 10.1007/s12035-020-01907-4
By:
- Comella-Bolla, Andrea;
- Orlandi, Javier G.;
- Miguez, Andrés;
- Straccia, Marco;
- García-Bravo, María;
- Bombau, Georgina;
- Galofré, Mireia;
- Sanders, Phil;
- Carrere, Jordi;
- Segovia, José Carlos;
- Blasi, Joan;
- Allen, Nicholas D.;
- Alberch, Jordi;
- Soriano, Jordi;
- Canals, Josep M.
Publication type:
Article

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