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In Silico Prediction of Major Clearance Pathways of Drugs among 9 Routes with Two-Step Support Vector Machines.
- Published in:
- Pharmaceutical Research, 2018, v. 35, n. 10, p. 1, doi. 10.1007/s11095-018-2479-1
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- Article
Virtual Clinical Studies to Examine the Probability Distribution of the AUC at Target Tissues Using Physiologically-Based Pharmacokinetic Modeling: Application to Analyses of the Effect of Genetic Polymorphism of Enzymes and Transporters on Irinotecan Induced Side Effects
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- Pharmaceutical Research, 2017, v. 34, n. 8, p. 1584, doi. 10.1007/s11095-017-2153-z
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- Article
Physiologically‐based pharmacokinetic modeling for investigating the effect of simeprevir on concomitant drugs and an endogenous biomarker of OATP1B.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 10, p. 1461, doi. 10.1002/psp4.13023
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- Article
Physiologically-Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine.
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- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 6, p. 396, doi. 10.1002/psp4.12398
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- Article
PBPK Modeling of Coproporphyrin I as an Endogenous Biomarker for Drug Interactions Involving Inhibition of Hepatic OATP1B1 and OATP1B3.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 11, p. 739, doi. 10.1002/psp4.12348
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- Article
Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype-Guided Dosing of Tamoxifen.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 7, p. 474, doi. 10.1002/psp4.12307
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- Article
Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 3, p. 186, doi. 10.1002/psp4.12275
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- Article