We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A microcirculation-guided trial: never trying is worse than failing.
- Authors
Bruno, Raphael Romano; Hernandez, Glenn; Thiele, Holger; Kattan, Eduardo; Jung, Christian
- Abstract
The comment discusses the Direct Assessment of Microcirculation In Shock (DAMIS) trial, which aimed to integrate microcirculatory information into treatment decisions for shock patients. The study used handheld video microscopy analysis to measure the percentage of perfused small vessels (sPPV) as an indicator of capillary perfusion. The comment responds to criticisms of the study, including the need for additional non-validated variables and a clear therapeutic strategy. The authors encourage further research and the design of a randomized controlled trial (RCT) to test the MicroTools algorithm for microcirculation analysis. The comment concludes by emphasizing the importance of attempting new approaches in order to advance medical knowledge.
- Subjects
VIDEO microscopy; RANDOMIZED controlled trials; SHOCK therapy; MICROCIRCULATION
- Publication
Intensive Care Medicine, 2023, Vol 49, Issue 12, p1555
- ISSN
0342-4642
- Publication type
Article
- DOI
10.1007/s00134-023-07245-y