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- Title
Subacute sensory neuronopathy secondary to dorsal root ganglionitis in primary Sjögren's syndrome.
- Authors
Malinow, K.; Yannakakis, G. D.; Glusman, S. M.; Edlow, D. W.; Griffin, J.; Pestronk, A.; Powell, D. L.; Ramsey-Goldman, R.; Eidelman, B. H.; Medsger, T. A.; Alexander, E. L.
- Abstract
Sensory neuropathies, particularly trigeminal neuropathy, have been recognized as neurological complications of Sjögren's syndrome, but the pathogenesis has not been established. We describe a woman with primary Sjögren's syndrome who developed a progressive debilitating subacute sensory neuronopathy. Results of electrophysiological studies were consistent with involvement of the trigeminal and dorsal root ganglia. A thoracic dorsal root ganglion biopsy showed lymphocytic infiltration and degeneration of ganglion cells. We believe that this is the first description of biopsy-documented dorsal root ganglionitis in a subacute sensory neuronopathy associated with Sjögren's syndrome and that the finding suggests an immunopathogenic basis.
- Publication
Annals of Neurology, 1986, Vol 20, Issue 4, p535
- ISSN
0364-5134
- Publication type
Article
- DOI
10.1002/ana.410200416