We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Evaluating the Utility of Rapid Point-of-Care Potassium Testing for the Early Identification of Hyperkalemia in Patients with Chronic Kidney Disease in the Emergency Department.
- Authors
Je Sung You; Yoo Seok Park; Hyun Soo Chung; Hye Sun Lee; Youngseon Joo; Jong Woo Park; Sung Phil Chung; Shin Ho Lee; Hahn Shick Lee
- Abstract
Purpose: Severe hyperkalemia leads to significant morbidity and mortality if it is not immediately recognized and treated. The concentration of potassium (K+) in the serum increases along with deteriorating renal function. The use of point-of-care K+ (POC-K+) in chronic kidney disease (CKD) could reduce the time for an accurate diagnosis and treatment, saving lives. We hypothesized that POC-K+ would accurately report K+ serum level without significant differences compared to reference testing, regardless of the renal function of the patient. Materials and Methods: The retrospective study was performed between January 2008 and September 2011 at an urban hospital in Seoul. The screening program using POC was conducted as a critical pathway for rapid evaluation and treatment of hyperkalemia since 2008. When a patient with CKD had at least one warning symptom or sign of hyperkalemia, both POC-K+ and routine laboratory tests were simultaneously ordered. The reliability of the two assays for serum-creatinine was assessed by intra-class correlation coefficient (ICC) analysis using absolute agreement of two-way mixed model. Results: High levels of reliability were found between POC and the laboratory reference tests for K+ (ICC=0.913, 95% CI 0.903-0.922) and between two tests for K+ according to changes in the serum-creatinine levels in CKD patients. Conclusion: The results of POC-K+ correlate well with values obtained from reference laboratory tests and coincide with changes in serum-creatinine of patients with CKD.
- Subjects
POTASSIUM; MEDICAL care; HYPERKALEMIA; KIDNEY diseases; MEDICAL emergencies; BLOOD serum analysis; SYMPTOMS; PATIENTS; DIAGNOSIS
- Publication
Yonsei Medical Journal, 2014, Vol 55, Issue 5, p1348
- ISSN
0513-5796
- Publication type
Article
- DOI
10.3349/ymj.2014.55.5.1348