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Coupled strategy based on regulator manipulation and medium optimization empowers the biosynthetic overproduction of lincomycin.
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- Synthetic & Systems Biotechnology, 2024, v. 9, n. 1, p. 134, doi. 10.1016/j.synbio.2024.01.004
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- Article
Sheep tail fat inhibits the proliferation of non-small-cell lung cancer cells in vitro and in vivo.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.917513
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- Article
Complete Genome Sequence of Clostridium kluyveri JZZ Applied in Chinese Strong-Flavor Liquor Production.
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- Current Microbiology, 2018, v. 75, n. 11, p. 1429, doi. 10.1007/s00284-018-1539-4
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- Article
SACE_0012, a TetR-Family Transcriptional Regulator, Affects the Morphogenesis of Saccharopolyspora erythraea.
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- Current Microbiology, 2013, v. 67, n. 6, p. 647, doi. 10.1007/s00284-013-0410-x
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- Article
Identification of SACE_7040, a Member of TetR Family Related to the Morphological Differentiation of Saccharopolyspora erythraea.
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- Current Microbiology, 2011, v. 63, n. 2, p. 121, doi. 10.1007/s00284-011-9943-z
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- Article
Transcriptome-guided target identification of the TetR-like regulator SACE_5754 and engineered overproduction of erythromycin in Saccharopolyspora erythraea.
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- Journal of Biological Engineering, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13036-018-0135-2
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- Article
TetR family regulator AbrT controls lincomycin production and morphological development in Streptomyces lincolnensis.
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- Microbial Cell Factories, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12934-024-02498-8
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- Article
A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.
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- Cell Research, 2015, v. 25, n. 11, p. 1237, doi. 10.1038/cr.2015.113
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- Article
Characterization and engineering of the Lrp/AsnC family regulator SACE_5717 for erythromycin overproduction in Saccharopolyspora erythraea.
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- Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 7, p. 1013, doi. 10.1007/s10295-019-02178-2
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- Article
Corrections to: Enhanced lincomycin production by co‑overexpression of metK1 and metK2 in Streptomyces lincolnensis.
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- 2018
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- Correction Notice
Enhanced lincomycin production by co-overexpression of <italic>metK1</italic> and <italic>metK2</italic> in <italic>Streptomyces lincolnensis</italic>.
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- Journal of Industrial Microbiology & Biotechnology, 2018, v. 45, n. 5, p. 345, doi. 10.1007/s10295-018-2029-1
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- Article
SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea.
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- Journal of Industrial Microbiology & Biotechnology, 2014, v. 41, n. 7, p. 1159, doi. 10.1007/s10295-014-1449-9
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- Article
Transcriptomics-Guided Investigation of the SLCG_Lrp Regulon Provides New Insights into Its Role for Lincomycin Biosynthesis.
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- Fermentation (Basel), 2023, v. 9, n. 4, p. 396, doi. 10.3390/fermentation9040396
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- Article
miR-526a regulates apoptotic cell growth in human carcinoma cells.
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- Molecular & Cellular Biochemistry, 2015, v. 407, n. 1/2, p. 69, doi. 10.1007/s11010-015-2455-6
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- Article
BRD4 Targets the KEAP1-Nrf2-G6PD Axis and Suppresses Redox Metabolism in Small Cell Lung Cancer.
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- Antioxidants, 2022, v. 11, n. 4, p. N.PAG, doi. 10.3390/antiox11040661
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- Article
Enrichment of C17:0-rich saturated fatty acids from sheep tail fat for adjuvant therapy of non-small-cell lung cancer.
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- Food Science & Biotechnology, 2024, v. 33, n. 8, p. 1947, doi. 10.1007/s10068-023-01504-w
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- Article
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
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- Nature, 2013, v. 500, n. 7461, p. 227, doi. 10.1038/nature12328
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- Article
High-efficiency genetic engineering toolkit for virus based on lambda red-mediated recombination.
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- Biotechnology Letters, 2023, v. 45, n. 10, p. 1327, doi. 10.1007/s10529-023-03412-9
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- Article
Stable overexpression of mutated PTEN in Chinese hamster ovary cells enhances their performance and therapeutic antibody production.
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- Biotechnology Journal, 2021, v. 16, n. 9, p. 1, doi. 10.1002/biot.202000623
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- Article
Synthetic biology of avermectin for production improvement and structure diversification.
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- Biotechnology Journal, 2014, v. 9, n. 3, p. 316, doi. 10.1002/biot.201200383
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- Article
The <italic>Arc</italic> Gene Confers Genetic Susceptibility to Alzheimer’s Disease in Han Chinese.
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- Molecular Neurobiology, 2018, v. 55, n. 2, p. 1217, doi. 10.1007/s12035-017-0397-6
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- Article
Crosstalk of TetR-like regulator SACE_4839 and a nitrogen regulator for erythromycin biosynthesis.
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- Applied Microbiology & Biotechnology, 2022, v. 106, n. 19/20, p. 6551, doi. 10.1007/s00253-022-12153-0
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- Article
Joint engineering of SACE_Lrp and its target MarR enhances the biosynthesis and export of erythromycin in Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2021, v. 105, n. 7, p. 2911, doi. 10.1007/s00253-021-11228-8
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- Article
Transcriptional regulation of a leucine-responsive regulatory protein for directly controlling lincomycin biosynthesis in Streptomyces lincolnensis.
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- Applied Microbiology & Biotechnology, 2020, v. 104, n. 6, p. 2575, doi. 10.1007/s00253-020-10381-w
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- Article
MiR-106b promotes therapeutic antibody expression in CHO cells by targeting deubiquitinase CYLD.
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- Applied Microbiology & Biotechnology, 2019, v. 103, n. 17, p. 7085, doi. 10.1007/s00253-019-10000-3
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- Article
Inactivation of deubiquitinase CYLD enhances therapeutic antibody production in Chinese hamster ovary cells.
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- Applied Microbiology & Biotechnology, 2018, v. 102, n. 14, p. 6081, doi. 10.1007/s00253-018-9070-x
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- Article
Characterization of an Lrp/AsnC family regulator SCO3361, controlling actinorhodin production and morphological development in Streptomyces coelicolor.
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- Applied Microbiology & Biotechnology, 2017, v. 101, n. 14, p. 5773, doi. 10.1007/s00253-017-8339-9
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- Article
Enhancement of antibiotic productions by engineered nitrate utilization in actinomycetes.
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- Applied Microbiology & Biotechnology, 2017, v. 101, n. 13, p. 5341, doi. 10.1007/s00253-017-8292-7
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- Article
In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2016, v. 100, n. 5, p. 2257, doi. 10.1007/s00253-015-7036-9
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- Article
A new salicylate synthase AmS is identified for siderophores biosynthesis in Amycolatopsis methanolica 239.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 14, p. 5895, doi. 10.1007/s00253-014-6370-7
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- Article
Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 6, p. 2683, doi. 10.1007/s00253-014-6255-9
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- Article
GlnR-mediated regulation of nitrogen metabolism in the actinomycete Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2014, v. 98, n. 18, p. 7935, doi. 10.1007/s00253-014-5878-1
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- Article
The leucine‐responsive regulatory protein SCAB_Lrp modulates thaxtomin biosynthesis, pathogenicity, and morphological development in Streptomyces scabies.
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- Molecular Plant Pathology, 2023, v. 24, n. 2, p. 167, doi. 10.1111/mpp.13285
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- Article
Identification of a common Ara h 3 epitope recognized by both the capture and the detection monoclonal antibodies in an ELISA detection kit.
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- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182935
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- Article
Heptadecanoic acid inhibits cell proliferation in PC-9 non-small-cell lung cancer cells with acquired gefitinib resistance.
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- Oncology Reports, 2019, v. 41, n. 6, p. 3499
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- Article