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- Title
The in vivo effect of UVB radiation on lymphocyte function.
- Authors
Morison, W. L.; Parrish, J. A.; Bloch, K. J.
- Abstract
The article focuses on the in vivo effect of UVB radiation on lymphocyte function. The effect of whole-body exposure to UVB radiation on the distribution and function of peripheral blood lymphocytes was investigated in ten normal volunteer subjects from whom informed consent had been obtained. Enumeration of T and B lymphocytes and measurement of the incorporation of tritiated thymidine into DNA following stimulation by phytohaemagglutinin were performed serially during the 72 h after exposure. Erythemogenic doses of UVB resulted in a significant depression of the proportion of T lymphocytes, a minimal depression of B lymphocytes and a decreased response to PHA stimulation.
- Subjects
ULTRAVIOLET radiation; LYMPHOCYTES; B cells; THYMIDINE; MENTAL depression; T cells
- Publication
British Journal of Dermatology, 1978, Vol 98, p21
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1978.tb13598.x