We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Emerging Roles of NPQ/Spexin in Physiology and Pathology.
- Authors
Lv, Shuang-Yu; Zhou, Yu-Chen; Zhang, Xiao-Mei; Chen, Wei-Dong; Wang, Yan-Dong
- Abstract
Spexin (SPX), also called neuropeptide Q (NPQ), is a novel endogenous neuropeptide. Spexin gene and protein are widely expressed in central nervous system and peripheral tissues in humans, rodents, goldfish, etc. A few of physiological and pathological roles of spexin are gradually emerged recently. This article summarized the roles of spexin in feeding behavior, gastrointestinal motility, obesity, diabetes, energy metabolism, endocrine, mental diseases, and cardiovascular function. Given the broad roles of spexin, this neuropeptide has attracted much interest from investigators and will be as a promising future target for novel therapeutic research and drug design.
- Subjects
PERIPHERAL nervous system; PHYSIOLOGY; MENTAL illness; CENTRAL nervous system; PATHOLOGY; ENERGY metabolism
- Publication
Frontiers in Pharmacology, 2019, pN.PAG
- ISSN
1663-9812
- Publication type
Article
- DOI
10.3389/fphar.2019.00457