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- Title
Sjögren syndrome complicated by mucosa-associated lymphoid tissue lymphoma and lymphocytic interstitial pneumonia.
- Authors
Ahmed, Fatma; Raslan, Osama; Muzaffar, Razi; Parkar, Nadeem; Marwaha, Nitin; Osman, Medhat M.; McConathy, Jonathan; Schillaci, Orazio
- Abstract
Sjögren syndrome (SS) is an autoimmune disease with exocrine glands dysfunction and multiorgan involvement. It is associated with increased risk of lymphoproliferative disorders, especially B-cell marginal zone lymphoma. While the role of F-18 Fluorodeoxyglucose position emission tomography/computed tomography (F-18 FDG PET/CT) for evaluation of lymphoma has been established, its use in patients with a chronic history of SS to evaluate for possible lymphoproliferative disorders or multiorgan involvement is limited. We present a case of chronic SS in which F-18 FDG PET/CT demonstrated FDG avid intraparotid and cervical lymph nodes pathologically proven to be mucosa-associated lymphoid tissue lymphoma. In addition, the patient had bibasilar cystic changes consistent with lymphocytic interstitial pneumonia.
- Subjects
SJOGREN'S syndrome; MUCOSA-associated lymphoid tissue lymphoma; PULMONARY fibrosis; PATIENTS; DISEASE risk factors
- Publication
Frontiers in Oncology, 2015, p1
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2015.00179