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- Title
Primary Diffuse Large B-cell Lymphoma Arising in the Tongue Accompanied by Ataxia-telangiectasia: A Case Report.
- Authors
HIROFUMI TOMIOKA; AYANO KANEOYA; YUMI MOCHIZUKI; HIROYUKI HARADA
- Abstract
Ataxia-telangiectasia (AT) is a rare autosomal recessive disorder that is characterized by progressive cerebellar ataxia, telangiectasia, immunodeficiency, and a predisposition to leukemia/lymphoma. Here we report a rare case of lymphoma of the tongue accompanied by AT. Tumour extirpation was performed and diffuse large B-cell lymphoma was diagnosed following pathologic examination. A whole-body survey showed no other enlarged lymph nodes or tumour. The female patient then received a modified dosage of COPAD (cyclophosphamide, vinblastine, pirarubicin, and prednisolone) plus rituximab to avoid severe complications. As of follow-up after 3 years and 5 months, she remains in complete remission. Patients showing AT need careful surveillance and long-term continuous follow-up.
- Subjects
LYMPHOMAS; MOVEMENT disorders; VASODILATION; ROTHMUND-Thomson syndrome; IMMUNOLOGICAL deficiency syndromes; DIAGNOSIS; CLINICAL medicine; MEDICAL care
- Publication
Journal of Clinical & Diagnostic Research, 2015, Vol 9, Issue 6, p25
- ISSN
0973-709X
- Publication type
Case Study
- DOI
10.7860/JCDR/2015/12121.6107