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- Title
Persistent Unexplained Transaminitis in COPA Syndrome.
- Authors
Thaivalappil, Silpa S.; Garrod, Andrea S.; Borowitz, Stephen M.; Watkin, Levi B.; Lawrence, Monica G.
- Abstract
To the Editor: COPA syndrome is a recently described monogenic immunodysregulatory syndrome. The most common clinical features of COPA syndrome are pulmonary hemorrhage, interstitial lung disease, arthritis, glomerular disease, and autoantibody development [[2]]. We present a case of a 2-year-old male with COPA syndrome manifesting as lymphocytic interstitial pneumonitis, peripheral blood B cell lymphocytosis, mediastinal lymphadenopathy and persistent, unexplained transaminitis.
- Subjects
SYNDROMES; HEAT shock proteins; TYPE I interferons; UNFOLDED protein response
- Publication
Journal of Clinical Immunology, 2021, Vol 41, Issue 1, p205
- ISSN
0271-9142
- Publication type
Letter
- DOI
10.1007/s10875-020-00832-4