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- Title
肿瘤相关成纤维细胞在肝细胞癌生长和转移中的作用.
- Authors
马德宁; 朱小东; 汤钊猷
- Abstract
The development and progression of tumors are closely related to the tumor mieroenvironment. As one of the most important components in tumor mieroenvironment, cancer - associated fibroblasts (CAFs) play an important role in carcinogenesis, angiogenesis, invasion, and metastasis of tumors. The role of CAFs in the development and progression of hepatocellular carcinoma (HCC) is reviewed by discussing how CAFs are recruited and activated in the tumor mieroenvironment and how CAFs promote tumor angiogenesis and regulate tumor immunity. This review may provide new approaches for the treatment of HCC.
- Publication
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi, 2014, Vol 30, Issue 9, p865
- ISSN
1001-5256
- Publication type
Article
- DOI
10.3696/j.issn.1001-5256.2014.09.007