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- Title
Schistosoma hematobium-associated glomerulopathy.
- Authors
Seck, S. M.; Sarr, M. L.; Dial, M. C.; Ka, E. F.
- Abstract
Schistosomiasis is the second most devastating tropical parasitic disease worldwide and is responsible for many urological complications. However, glomerular injury is a rare complication mainly described with Schistosoma mansoni. We report a case of membranoproliferative glomerulonephritis (MPGN) associated with Schistosoma hematobium infection in a young Senegalese boy living in a rural area. Clinical presentation was with steroid-resistant with nephrotic syndrome. Renal biopsy showed type 1 MPGN with the presence of S. hematobium eggs surrounded by a gigantocellular granuloma. Despite therapy with antihelminthic and immunosuppressive drugs, evolution was characterized by progression to end-stage renal disease over 1 year. More efforts should be made on the prevention and early detection of schistosomiasis among at-risk populations.
- Subjects
SCHISTOSOMIASIS diagnosis; NEPHROTIC syndrome diagnosis; SCHISTOSOMIASIS
- Publication
Indian Journal of Nephrology, 2011, Vol 21, Issue 3, p201
- ISSN
0971-4065
- Publication type
Article
- DOI
10.4103/0971-4065.78076