We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
In-vitro activity of teicoplanin and ceftriaxone in combination against pathogens involved in paediatric bone and joint infections.
- Authors
Lhopital, Sylvie; Bonacorsi, Stéphane; Doit, Catherine; Sandin, Anna; Bingen, Edouard; Lhopital, S; Bonacorsi, S; Doit, C; Sandin, A; Bingen, E
- Abstract
We investigated the combination of teicoplanin and ceftriaxone for its bactericidal activity against Staphylococcus aureus, Haemophilus influenzae type b and Streptococcus pneumoniae isolated from bone and joint infections in children. An increase in bactericidal activity was observed against isolates of S. aureus and H. influenzae when the antibiotics were tested at fractional MICs whereas indifference was observed at their MICs. Similar results were obtained at fractional MICs against S. pneumoniae, but the bactericidal activity fell by more than 1 × log 10 cfu/mL when the antibiotics were tested at or above their MICs.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1996, Vol 38, Issue 4, p713
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/38.4.713