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Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
Published in:
2008
By:
- Kharas, Michael G.;
- Janes, Matthew R.;
- Scarfone, Vanessa M.;
- Lilly, Michael B.;
- Knight, Zachary A.;
- Shokat, Kevan M.;
- Fruman, David A.
Publication type:
journal article
Advanced glycation end products are elevated in estrogen receptor-positive breast cancer patients, alter response to therapy, and can be targeted by lifestyle intervention.
Published in:
Breast Cancer Research & Treatment, 2019, v. 173, n. 3, p. 559, doi. 10.1007/s10549-018-4992-7
By:
- Walter, Katherine R.;
- Ford, Marvella E.;
- Gregoski, Mathew J.;
- Kramer, Rita M.;
- Knight, Kendrea D.;
- Spruill, Laura;
- Nogueira, Lourdes M.;
- Krisanits, Bradley A.;
- Phan, Van;
- La Rue, Amanda C.;
- Lilly, Michael B.;
- Ambs, Stefan;
- Chan, King;
- Turner, Tonya F.;
- Varner, Heidi;
- Singh, Shweta;
- Uribarri, Jaime;
- Garrett-Mayer, Elizabeth;
- Armeson, Kent E.;
- Hilton, Ebony J.
Publication type:
Article
Genomic amplifications identified by circulating tumor DNA analysis guide prognosis in metastatic castration-resistant prostate cancer.
Published in:
Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2023.1202277
By:
- Dincman, Toros A.;
- Karam, Joseph A. Q.;
- Giordano, Antonio;
- Hong Li;
- Drusbosky, Leylah M.;
- Gourdin, Theodore S.;
- Howe, Philip H.;
- Lilly, Michael B.
Publication type:
Article
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Published in:
Nature Medicine, 2010, v. 16, n. 2, p. 205, doi. 10.1038/nm.2091
By:
- Janes, Matthew R.;
- Limon, Jose J.;
- So, Lomon;
- Jing Chen;
- Lim, Raymond J.;
- Chavez, Melissa A.;
- Vu, Collin;
- Lilly, Michael B.;
- Mallya, Sharmila;
- Ong, S. Tiong;
- Konopleva, Marina;
- Martin, Michael B.;
- Ren, Pingda;
- Yi Liu;
- Rommel, Christian;
- Fruman, David A.
Publication type:
Article
Generation of “Virtual” Control Groups for Single Arm Prostate Cancer Adjuvant Trials.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085010
By:
- Jia, Zhenyu;
- Lilly, Michael B.;
- Koziol, James A.;
- Chen, Xin;
- Xia, Xiao-Qin;
- Wang, Yipeng;
- Skarecky, Douglas;
- Sutton, Manuel;
- Sawyers, Anne;
- Ruckle, Herbert;
- Carpenter, Philip M.;
- Wang-Rodriguez, Jessica;
- Jiang, Jun;
- Deng, Mingsen;
- Pan, Cong;
- Zhu, Jian-guo;
- McLaren, Christine E.;
- Gurley, Michael J.;
- Lee, Chung;
- McClelland, Michael
Publication type:
Article
Plasma-Derived Exosomal Survivin, a Plausible Biomarker for Early Detection of Prostate Cancer.
Published in:
PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046737
By:
- Khan, Salma;
- Jutzy, Jessica M. S.;
- Valenzuela, Malyn May A.;
- Turay, David;
- Aspe, Jonathan R.;
- Ashok, Arjun;
- Mirshahidi, Saied;
- Mercola, Dan;
- Lilly, Michael B.;
- Wall, Nathan R.
Publication type:
Article
Kava Components Down-Regulate Expression of AR and AR Splice Variants and Reduce Growth in Patient-Derived Prostate Cancer Xenografts in Mice.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031213
By:
- Xuesen Li;
- Zhongbo Liu;
- Xia Xu;
- Blair, Christopher A.;
- Zheng Sun;
- Jun Xie;
- Lilly, Michael B.;
- Xiaolin Zi
Publication type:
Article
A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients.
Published in:
Clinical & Translational Medicine, 2024, v. 14, n. 3, p. 1, doi. 10.1002/ctm2.1627
By:
- Lilly, Michael B.;
- Wu, Chunli;
- Ke, Yu;
- Chen, Wen‐Pin;
- Soloff, Adam C.;
- Armeson, Kent;
- Yokoyama, Noriko N.;
- Li, Xiaotian;
- Song, Liankun;
- Yuan, Ying;
- McLaren, Christine E.;
- Zi, Xiaolin
Publication type:
Article
Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
Published in:
2017
By:
- Kharas, Michael G;
- Janes, Matthew R;
- Scarfone, Vanessa M;
- Lilly, Michael B;
- Knight, Zachary A;
- Shokat, Kevan M;
- Fruman, David A
Publication type:
journal article
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β.
Published in:
Science Translational Medicine, 2020, v. 12, n. 525, p. 1, doi. 10.1126/scitranslmed.aay4860
By:
- Metelli, Alessandra;
- Wu, Bill X.;
- Riesenberg, Brian;
- Guglietta, Silvia;
- Huck, John D.;
- Mills, Catherine;
- Li, Anqi;
- Rachidi, Saleh;
- Krieg, Carsten;
- Rubinstein, Mark P.;
- Gewirth, Daniel T.;
- Sun, Shaoli;
- Lilly, Michael B.;
- Wahlquist, Amy H.;
- Carbone, David P.;
- Yang, Yiping;
- Liu, Bei;
- Li, Zihai
Publication type:
Article
Differential expression of peroxiredoxins in prostate cancer: Consistent upregulation of PRDX3 and PRDX4.
Published in:
Prostate, 2011, v. 71, n. 7, p. 755, doi. 10.1002/pros.21292
By:
- Basu, Anamika;
- Banerjee, Hiya;
- Rojas, Heather;
- Martinez, Shannalee R.;
- Roy, Sourav;
- Jia, Zhenyu;
- Lilly, Michael B.;
- De León, Marino;
- Casiano, Carlos A.
Publication type:
Article
Racial Distribution of Neighborhood-Level Social Deprivation in a Retrospective Cohort of Prostate Cancer Survivors.
Published in:
Diseases, 2022, v. 10, n. 4, p. 75, doi. 10.3390/diseases10040075
By:
- Babatunde, Oluwole Adeyemi;
- Pearce, John L.;
- Jefferson, Melanie S.;
- Frey, Lewis J.;
- Angel, Peggi M.;
- Drake, Richard R.;
- Allen, Caitlin G.;
- Lilly, Michael B.;
- Savage, Stephen J.;
- Hughes Halbert, Chanita
Publication type:
Article
Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2012, v. 26, n. 10, p. 1, doi. 10.1038/leu.2012.276
By:
- Janes, Matthew R.;
- Vu, Collin;
- Mallya, Sharmila;
- Marie Shieh, Marie;
- Limon, Jose J.;
- Lian-Sheng Li;
- Jessen, Katti A.;
- Martin, Michael B.;
- Pingda Ren;
- Lilly, Michael B.;
- Sender, Leonard;
- Yi Liu;
- Rommel, Christian;
- Fruman, David A.
Publication type:
Article
Development of cell-penetrating bispecific antibodies targeting the N-terminal domain of androgen receptor for prostate cancer therapy.
Published in:
PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 12, p. 1, doi. 10.1093/protein/gzx058
By:
- Goicochea, Nancy L.;
- Garnovskaya, Maria;
- Blanton, Mary G.;
- Chan, Grace;
- Weisbart, Richard;
- Lilly, Michael B.
Publication type:
Article
Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study.
Published in:
American Journal of Hematology, 2010, v. 85, n. 3, p. 164, doi. 10.1002/ajh.21615
By:
- Lilly, Michael B.;
- Ottmann, Oliver G.;
- Shah, Neil P.;
- Larson, Richard A.;
- Reiffers, Josy J.;
- Ehninger, Gerhard;
- Müller, Martin C.;
- Charbonnier, Aude;
- Bullorsky, Eduardo;
- Dombret, Herve;
- Brigid Bradley-Garelik, Mary;
- Zhu, Chao;
- Martinelli, Giovanni
Publication type:
Article
Circulating tumor DNA alterations in patients with metastatic castration-resistant prostate cancer.
Published in:
2019
By:
- Sonpavde, Guru;
- Agarwal, Neeraj;
- Pond, Gregory Russell;
- Nagy, Rebecca J.;
- Nussenzveig, Roberto H.;
- Hahn, Andrew W.;
- Sartor, Oliver;
- Gourdin, Theodore Stewart;
- Nandagopal, Lakshminarayanan;
- Ledet, Elisa M.;
- Naik, Gurudatta;
- Armstrong, Andrew J.;
- Wang, Jue;
- Bilen, Mehmet Asim;
- Gupta, Shilpa;
- Grivas, Petros;
- Pal, Sumanta K.;
- Lanman, Richard B.;
- Talasaz, AmirAli;
- Lilly, Michael B.
Publication type:
journal article
PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.
Published in:
International Journal of Experimental Pathology, 2010, v. 91, n. 1, p. 34, doi. 10.1111/j.1365-2613.2009.00673.x
By:
- Min En Nga;
- Nu Nu Ma Swe;
- Kang Ting Chen;
- Shen, Liang;
- Lilly, Michael B.;
- Chan, Siew Pang;
- Salto-Tellez, Manuel;
- Das, Kakoli
Publication type:
Article
Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration‐resistant prostate cancer.
Published in:
Prostate, 2022, v. 82, n. 13, p. 1264, doi. 10.1002/pros.24400
By:
- Bray, Alexander W.;
- Duan, Rong;
- Malalur, Pannaga;
- Drusbosky, Leylah M.;
- Gourdin, Theodore S.;
- Hill, Elizabeth G.;
- Lilly, Michael B.
Publication type:
Article
Comprehensive Genomic Profiling of Cell-Free DNA in Men With Advanced Prostate Cancer: Differences in Genomic Landscape Based on Race.
Published in:
Oncologist, 2022, v. 27, n. 10, p. e815, doi. 10.1093/oncolo/oyac176
By:
- Zimmerman, Raquel;
- Bilen, Mehmet A;
- Heath, Elisabeth I;
- Nandagopal, Lakshminarayanan;
- Swami, Umang;
- Kessel, Adam;
- Jaeger, Ellen;
- Wesolowski, Sergiusz;
- Hernanadez, Edgar J;
- Chipman, Jonathan;
- Mack, Alleda;
- Ravindranathan, Deepak;
- Maughan, Benjamin L;
- Nussenzveig, Roberto;
- Yandell, Mark;
- Kohli, Manish;
- Lilly, Michael B;
- Sartor, A Oliver;
- Agarwal, Neeraj;
- Barata, Pedro C
Publication type:
Article
Comprehensive Genomic Profiling of Cell-Free DNA in Men With Advanced Prostate Cancer: Differences in Genomic Landscape Based on Race.
Published in:
Oncologist, 2022, v. 27, n. 9, p. e815, doi. 10.1093/oncolo/oyac176
By:
- Zimmerman, Raquel;
- Bilen, Mehmet A;
- Heath, Elisabeth I;
- Nandagopal, Lakshminarayanan;
- Swami, Umang;
- Kessel, Adam;
- Jaeger, Ellen;
- Wesolowski, Sergiusz;
- Hernanadez, Edgar J;
- Chipman, Jonathan;
- Mack, Alleda;
- Ravindranathan, Deepak;
- Maughan, Benjamin L;
- Nussenzveig, Roberto;
- Yandell, Mark;
- Kohli, Manish;
- Lilly, Michael B;
- Sartor, A Oliver;
- Agarwal, Neeraj;
- Barata, Pedro C
Publication type:
Article
Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer.
Published in:
Oncologist, 2020, v. 25, n. 4, p. 327, doi. 10.1634/theoncologist.2019-0115
By:
- Ledet, Elisa M.;
- Lilly, Michael B.;
- Sonpavde, Guru;
- Lin, Edwin;
- Nussenzveig, Roberto H.;
- Barata, Pedro C.;
- Yandell, Mark;
- Nagy, Rebecca J.;
- Kiedrowski, Lesli;
- Agarwal, Neeraj;
- Sartor, Oliver
Publication type:
Article

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